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Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis.
Gerboth S, Frittoli E, Palamidessi A, Baltanas FC, Salek M, Rappsilber J, Giuliani C, Troglio F, Rolland Y, Pruneri G, Kreutmair S, Pallavicini I, Zobel M, Cinquanta M, Minucci S, Gomez C, Santos E, Illert AL, Scita G. Gerboth S, et al. Among authors: baltanas fc. Leukemia. 2018 Mar;32(3):820-827. doi: 10.1038/leu.2017.267. Epub 2017 Aug 18. Leukemia. 2018. PMID: 28819285 Free PMC article.
Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.
Liceras-Boillos P, Jimeno D, García-Navas R, Lorenzo-Martín LF, Menacho-Marquez M, Segrelles C, Gómez C, Calzada N, Fuentes-Mateos R, Paramio JM, Bustelo XR, Baltanás FC, Santos E. Liceras-Boillos P, et al. Among authors: baltanas fc. Mol Cell Biol. 2018 Jul 30;38(16):e00049-18. doi: 10.1128/MCB.00049-18. Print 2018 Aug 15. Mol Cell Biol. 2018. PMID: 29844066 Free PMC article.
SOS GEFs in health and disease.
Baltanás FC, Zarich N, Rojas-Cabañeros JM, Santos E. Baltanás FC, et al. Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188445. doi: 10.1016/j.bbcan.2020.188445. Epub 2020 Oct 6. Biochim Biophys Acta Rev Cancer. 2020. PMID: 33035641 Free article. Review.
Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis.
Baltanás FC, Mucientes-Valdivieso C, Lorenzo-Martín LF, Fernández-Parejo N, García-Navas R, Segrelles C, Calzada N, Fuentes-Mateos R, Paramio JM, Bustelo XR, Santos E. Baltanás FC, et al. Cancers (Basel). 2021 Apr 29;13(9):2152. doi: 10.3390/cancers13092152. Cancers (Basel). 2021. PMID: 33946974 Free PMC article.
28 results