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Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model.
Borg DJ, Faridi P, Giam KL, Reeves P, Fotheringham AK, McCarthy DA, Leung S, Ward MS, Harcourt BE, Ayala R, Scheijen JL, Briskey D, Dudek NL, Schalkwijk CG, Steptoe R, Purcell AW, Forbes JM. Borg DJ, et al. Among authors: harcourt be. Metabolites. 2021 Jun 28;11(7):426. doi: 10.3390/metabo11070426. Metabolites. 2021. PMID: 34203471 Free PMC article.
RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.
Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME, Forbes JM. Coughlan MT, et al. Among authors: harcourt be. J Am Soc Nephrol. 2009 Apr;20(4):742-52. doi: 10.1681/ASN.2008050514. Epub 2009 Jan 21. J Am Soc Nephrol. 2009. PMID: 19158353 Free PMC article.
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.
Tan AL, Sourris KC, Harcourt BE, Thallas-Bonke V, Penfold S, Andrikopoulos S, Thomas MC, O'Brien RC, Bierhaus A, Cooper ME, Forbes JM, Coughlan MT. Tan AL, et al. Among authors: harcourt be. Am J Physiol Renal Physiol. 2010 Mar;298(3):F763-70. doi: 10.1152/ajprenal.00591.2009. Epub 2009 Dec 16. Am J Physiol Renal Physiol. 2010. PMID: 20015941 Free article.
Targeted reduction of advanced glycation improves renal function in obesity.
Harcourt BE, Sourris KC, Coughlan MT, Walker KZ, Dougherty SL, Andrikopoulos S, Morley AL, Thallas-Bonke V, Chand V, Penfold SA, de Courten MP, Thomas MC, Kingwell BA, Bierhaus A, Cooper ME, de Courten B, Forbes JM. Harcourt BE, et al. Kidney Int. 2011 Jul;80(2):190-8. doi: 10.1038/ki.2011.57. Epub 2011 Mar 16. Kidney Int. 2011. PMID: 21412218 Free article. Clinical Trial.
33 results