O'Connor RS - Search Results

1

Beyond the Lactate Paradox: How Lactate and Acidity Impact T Cell Therapies against Cancer.

Tu VY, Ayari A, O'Connor RS. Tu VY, et al. Antibodies (Basel). 2021 Jun 28;10(3):25. doi: 10.3390/antib10030025. Antibodies (Basel). 2021. PMID: 34203136 Free PMC article. Review.

2

Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design.

Ghassemi S, Martinez-Becerra FJ, Master AM, Richman SA, Heo D, Leferovich J, Tu Y, García-Cañaveras JC, Ayari A, Lu Y, Wang A, Rabinowitz JD, Milone MC, June CH, O'Connor RS. Ghassemi S, et al. Mol Ther Methods Clin Dev. 2020 Jul 9;18:595-606. doi: 10.1016/j.omtm.2020.07.008. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32775494 Free PMC article.

3

Citius, Altius, Fortius: Performance in a Bottle for CAR T-Cells.

Ayari A, O'Connor RS. Ayari A, et al. J Clin Haematol. 2020;1(3):103-106. doi: 10.33696/haematology.1.015. J Clin Haematol. 2020. PMID: 33554221 Free PMC article. No abstract available.

4

Checkmate: Metabolic flexibility with a STING in its tail.

O'Connor RS. O'Connor RS. Sci Adv. 2023 Dec 8;9(49):eadm6816. doi: 10.1126/sciadv.adm6816. Epub 2023 Dec 6. Sci Adv. 2023. PMID: 38055812 Free PMC article. Review.

5

CAR T cell immunotherapy for human cancer.

June CH, O'Connor RS, Kawalekar OU, Ghassemi S, Milone MC. June CH, et al. Science. 2018 Mar 23;359(6382):1361-1365. doi: 10.1126/science.aar6711. Science. 2018. PMID: 29567707 Review.

6

Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells.

O'Connor RS, Milone MC. O'Connor RS, et al. Methods Mol Biol. 2020;2097:83-90. doi: 10.1007/978-1-0716-0203-4_5. Methods Mol Biol. 2020. PMID: 31776920 Free PMC article.

7

Human chimeric antigen receptor macrophages for cancer immunotherapy.

Klichinsky M, Ruella M, Shestova O, Lu XM, Best A, Zeeman M, Schmierer M, Gabrusiewicz K, Anderson NR, Petty NE, Cummins KD, Shen F, Shan X, Veliz K, Blouch K, Yashiro-Ohtani Y, Kenderian SS, Kim MY, O'Connor RS, Wallace SR, Kozlowski MS, Marchione DM, Shestov M, Garcia BA, June CH, Gill S. Klichinsky M, et al. Nat Biotechnol. 2020 Aug;38(8):947-953. doi: 10.1038/s41587-020-0462-y. Epub 2020 Mar 23. Nat Biotechnol. 2020. PMID: 32361713 Free PMC article.

8

Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy.

Huarte E, O'Connor RS, Peel MT, Nunez-Cruz S, Leferovich J, Juvekar A, Yang YO, Truong L, Huang T, Naim A, Milone MC, Smith PA. Huarte E, et al. Clin Cancer Res. 2020 Dec 1;26(23):6299-6309. doi: 10.1158/1078-0432.CCR-20-1739. Epub 2020 Sep 30. Clin Cancer Res. 2020. PMID: 32998963 Free PMC article.

9

Lingering effects of chemotherapy on mature T cells impair proliferation.

Das RK, O'Connor RS, Grupp SA, Barrett DM. Das RK, et al. Blood Adv. 2020 Oct 13;4(19):4653-4664. doi: 10.1182/bloodadvances.2020001797. Blood Adv. 2020. PMID: 33002133 Free PMC article.

10

CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy.

Rodriguez-Garcia A, Lynn RC, Poussin M, Eiva MA, Shaw LC, O'Connor RS, Minutolo NG, Casado-Medrano V, Lopez G, Matsuyama T, Powell DJ Jr. Rodriguez-Garcia A, et al. Nat Commun. 2021 Feb 9;12(1):877. doi: 10.1038/s41467-021-20893-2. Nat Commun. 2021. PMID: 33563975 Free PMC article.

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