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A novel approach for studying receptor-ligand interactions on living cells surface by using NUS/T1ρ-NMR methodologies combined with computational techniques: The RGDechi15D-αvβ5 integrin complex.
Farina B, Andrea C, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Paladino A, Acconcia C, Gentile MT, Saviano M, Fattorusso R, Zaccaro L, Russo L. Farina B, et al. Among authors: comegna d. Comput Struct Biotechnol J. 2021 May 29;19:3303-3318. doi: 10.1016/j.csbj.2021.05.047. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34188779 Free PMC article.
[99mTc][Tc(N)PNP43]-Labeled RGD Peptides As New Probes for a Selective Detection of αvβ3 Integrin: Synthesis, Structure-Activity and Pharmacokinetic Studies.
Bolzati C, Salvarese N, Carpanese D, Seraglia R, Meléndez-Alafort L, Rosato A, Capasso D, Saviano M, Del Gatto A, Comegna D, Zaccaro L. Bolzati C, et al. Among authors: comegna d. J Med Chem. 2018 Nov 8;61(21):9596-9610. doi: 10.1021/acs.jmedchem.8b01075. Epub 2018 Oct 17. J Med Chem. 2018. PMID: 30278131
Gold-Speckled SPION@SiO2 Nanoparticles Decorated with Thiocarbohydrates for ASGPR1 Targeting: Towards HCC Dual Mode Imaging Potential Applications.
Siciliano G, Corricelli M, Iacobazzi RM, Canepa F, Comegna D, Fanizza E, Del Gatto A, Saviano M, Laquintana V, Comparelli R, Mascolo G, Murgolo S, Striccoli M, Agostiano A, Denora N, Zaccaro L, Curri ML, Depalo N. Siciliano G, et al. Among authors: comegna d. Chemistry. 2020 Aug 26;26(48):11048-11059. doi: 10.1002/chem.202002142. Epub 2020 Jul 30. Chemistry. 2020. PMID: 32628283
NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging.
Depalo N, Corricelli M, De Paola I, Valente G, Iacobazzi RM, Altamura E, Debellis D, Comegna D, Fanizza E, Denora N, Laquintana V, Mavelli F, Striccoli M, Saviano M, Agostiano A, Del Gatto A, Zaccaro L, Curri ML. Depalo N, et al. Among authors: comegna d. ACS Appl Mater Interfaces. 2017 Dec 13;9(49):43113-43126. doi: 10.1021/acsami.7b14155. Epub 2017 Dec 1. ACS Appl Mater Interfaces. 2017. PMID: 29148709
16 results