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An adverse outcome pathway on the disruption of retinoic acid metabolism leading to developmental craniofacial defects.
Menegola E, Veltman CHJ, Battistoni M, Di Renzo F, Moretto A, Metruccio F, Beronius A, Zilliacus J, Kyriakopoulou K, Spyropoulou A, Machera K, van der Ven LTM, Luijten M. Menegola E, et al. Among authors: spyropoulou a. Toxicology. 2021 Jun 30;458:152843. doi: 10.1016/j.tox.2021.152843. Epub 2021 Jun 26. Toxicology. 2021. PMID: 34186166
Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach.
Alarcan J, de Sousa G, Katsanou ES, Spyropoulou A, Batakis P, Machera K, Rahmani R, Lampen A, Braeuning A, Lichtenstein D. Alarcan J, et al. Among authors: spyropoulou a. Arch Toxicol. 2022 Jan;96(1):211-229. doi: 10.1007/s00204-021-03182-1. Epub 2021 Nov 15. Arch Toxicol. 2022. PMID: 34778935 Free PMC article.
Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole.
Luckert C, Braeuning A, de Sousa G, Durinck S, Katsanou ES, Konstantinidou P, Machera K, Milani ES, Peijnenburg AACM, Rahmani R, Rajkovic A, Rijkers D, Spyropoulou A, Stamou M, Stoopen G, Sturla S, Wollscheid B, Zucchini-Pascal N, Lampen A. Luckert C, et al. Among authors: spyropoulou a. Chem Res Toxicol. 2018 Aug 20;31(8):784-798. doi: 10.1021/acs.chemrestox.8b00112. Epub 2018 Jul 11. Chem Res Toxicol. 2018. PMID: 29995386
An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro.
Lichtenstein D, Luckert C, Alarcan J, de Sousa G, Gioutlakis M, Katsanou ES, Konstantinidou P, Machera K, Milani ES, Peijnenburg A, Rahmani R, Rijkers D, Spyropoulou A, Stamou M, Stoopen G, Sturla SJ, Wollscheid B, Zucchini-Pascal N, Braeuning A, Lampen A. Lichtenstein D, et al. Among authors: spyropoulou a. Food Chem Toxicol. 2020 May;139:111283. doi: 10.1016/j.fct.2020.111283. Epub 2020 Mar 19. Food Chem Toxicol. 2020. PMID: 32201337
Emerging role of linker histone variant H1x as a biomarker with prognostic value in astrocytic gliomas. A multivariate analysis including trimethylation of H3K9 and H4K20.
Sepsa A, Levidou G, Gargalionis A, Adamopoulos C, Spyropoulou A, Dalagiorgou G, Thymara I, Boviatsis E, Themistocleous MS, Petraki K, Vrettakos G, Samaras V, Zisakis A, Patsouris E, Piperi C, Korkolopoulou P. Sepsa A, et al. Among authors: spyropoulou a. PLoS One. 2015 Jan 20;10(1):e0115101. doi: 10.1371/journal.pone.0115101. eCollection 2015. PLoS One. 2015. PMID: 25602259 Free PMC article.
Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis.
Dalagiorgou G, Piperi C, Adamopoulos C, Georgopoulou U, Gargalionis AN, Spyropoulou A, Zoi I, Nokhbehsaim M, Damanaki A, Deschner J, Basdra EK, Papavassiliou AG. Dalagiorgou G, et al. Among authors: spyropoulou a. Cell Mol Life Sci. 2017 Mar;74(5):921-936. doi: 10.1007/s00018-016-2394-8. Epub 2016 Oct 3. Cell Mol Life Sci. 2017. PMID: 27699453 Free PMC article.
Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development.
El-Habr EA, Levidou G, Trigka EA, Sakalidou J, Piperi C, Chatziandreou I, Spyropoulou A, Soldatos R, Tomara G, Petraki K, Samaras V, Zisakis A, Varsos V, Vrettakos G, Boviatsis E, Patsouris E, Saetta AA, Korkolopoulou P. El-Habr EA, et al. Among authors: spyropoulou a. Virchows Arch. 2014 Oct;465(4):473-85. doi: 10.1007/s00428-014-1641-3. Epub 2014 Aug 22. Virchows Arch. 2014. PMID: 25146167
60 results