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Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production.
Badou A, Savignac M, Moreau M, Leclerc C, Foucras G, Cassar G, Paulet P, Lagrange D, Druet P, Guéry JC, Pelletier L. Badou A, et al. Among authors: guery jc. Eur J Immunol. 2001 Aug;31(8):2487-96. doi: 10.1002/1521-4141(200108)31:8<2487::aid-immu2487>3.0.co;2-l. Eur J Immunol. 2001. PMID: 11500833 Free article.
Calcium channel blocker prevents T helper type 2 cell-mediated airway inflammation.
Gomes B, Cabral MD, Gallard A, Savignac M, Paulet P, Druet P, Mariamé B, Moreau M, Leclerc C, Guéry JC, Pelletier L. Gomes B, et al. Among authors: guery jc. Am J Respir Crit Care Med. 2007 Jun 1;175(11):1117-24. doi: 10.1164/rccm.200607-1026OC. Epub 2007 Mar 8. Am J Respir Crit Care Med. 2007. PMID: 17347497
Dihydropyridine receptor blockade in the treatment of asthma.
Pelletier L, Guéry JC. Pelletier L, et al. Among authors: guery jc. Recent Pat Inflamm Allergy Drug Discov. 2008 Jun;2(2):109-16. doi: 10.2174/187221308784543638. Recent Pat Inflamm Allergy Drug Discov. 2008. PMID: 19075999 Review.
Knocking down Cav1 calcium channels implicated in Th2 cell activation prevents experimental asthma.
Cabral MD, Paulet PE, Robert V, Gomes B, Renoud ML, Savignac M, Leclerc C, Moreau M, Lair D, Langelot M, Magnan A, Yssel H, Mariamé B, Guéry JC, Pelletier L. Cabral MD, et al. Among authors: guery jc. Am J Respir Crit Care Med. 2010 Jun 15;181(12):1310-7. doi: 10.1164/rccm.200907-1166OC. Epub 2010 Feb 18. Am J Respir Crit Care Med. 2010. PMID: 20167851
116 results