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The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells.
Front Oncol. 2021 Jun 11;11:642603. doi: 10.3389/fonc.2021.642603. eCollection 2021.
Front Oncol. 2021.
PMID: 34178628
Free PMC article.
Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Isermann T, Şener ÖÇ, Stender A, Klemke L, Winkler N, Neesse A, Li J, Wegwitz F, Moll UM, Schulz-Heddergott R.
Isermann T, et al. Among authors: klemke l.
Nat Commun. 2021 Jun 29;12(1):4019. doi: 10.1038/s41467-021-24064-1.
Nat Commun. 2021.
PMID: 34188043
Free PMC article.
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Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer.
Klemke L, De Oliveira T, Witt D, Winkler N, Bohnenberger H, Bucala R, Conradi LC, Schulz-Heddergott R.
Klemke L, et al.
Cell Death Dis. 2021 Feb 4;12(2):155. doi: 10.1038/s41419-021-03426-z.
Cell Death Dis. 2021.
PMID: 33542244
Free PMC article.
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Preparation and Cultivation of Colonic and Small Intestinal Murine Organoids Including Analysis of Gene Expression and Organoid Viability.
Klemke L, Blume JP, De Oliveira T, Schulz-Heddergott R.
Klemke L, et al.
Bio Protoc. 2022 Jan 20;12(2):e4298. doi: 10.21769/BioProtoc.4298. eCollection 2022 Jan 20.
Bio Protoc. 2022.
PMID: 35127988
Free PMC article.
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The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models.
Stegmann KM, Dickmanns A, Gerber S, Nikolova V, Klemke L, Manzini V, Schlösser D, Bierwirth C, Freund J, Sitte M, Lugert R, Salinas G, Meister TL, Pfaender S, Görlich D, Wollnik B, Groß U, Dobbelstein M.
Stegmann KM, et al. Among authors: klemke l.
Virus Res. 2021 Sep;302:198469. doi: 10.1016/j.virusres.2021.198469. Epub 2021 Jun 6.
Virus Res. 2021.
PMID: 34090962
Free PMC article.
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Evolution of neurodegeneration in patients with normal pressure hydrocephalus: a monocentric follow up study.
Klemke LL, Müller-Schmitz K, Kolman A, Seitz RJ.
Klemke LL, et al.
Neurol Res Pract. 2023 Sep 7;5(1):52. doi: 10.1186/s42466-023-00272-6.
Neurol Res Pract. 2023.
PMID: 37674250
Free PMC article.
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