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A strategy to reduce the carbon footprint of clinical trials.
Adshead F, Al-Shahi Salman R, Aumonier S, Collins M, Hood K, McNamara C, Moore K, Smith R, Sydes MR, Williamson PR. Adshead F, et al. Among authors: sydes mr. Lancet. 2021 Jul 24;398(10297):281-282. doi: 10.1016/S0140-6736(21)01384-2. Epub 2021 Jun 23. Lancet. 2021. PMID: 34171294 No abstract available.
More multiarm randomised trials of superiority are needed.
Parmar MK, Carpenter J, Sydes MR. Parmar MK, et al. Among authors: sydes mr. Lancet. 2014 Jul 26;384(9940):283-4. doi: 10.1016/S0140-6736(14)61122-3. Lancet. 2014. PMID: 25066148 No abstract available.
Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform.
Treweek S, Altman DG, Bower P, Campbell M, Chalmers I, Cotton S, Craig P, Crosby D, Davidson P, Devane D, Duley L, Dunn J, Elbourne D, Farrell B, Gamble C, Gillies K, Hood K, Lang T, Littleford R, Loudon K, McDonald A, McPherson G, Nelson A, Norrie J, Ramsay C, Sandercock P, Shanahan DR, Summerskill W, Sydes M, Williamson P, Clarke M. Treweek S, et al. Trials. 2015 Jun 5;16:261. doi: 10.1186/s13063-015-0776-0. Trials. 2015. PMID: 26044814 Free PMC article.
Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.
Parmar MK, Sydes MR, Cafferty FH, Choodari-Oskooei B, Langley RE, Brown L, Phillips PP, Spears MR, Rowley S, Kaplan R, James ND, Maughan T, Paton N, Royston PJ. Parmar MK, et al. Among authors: sydes mr. Clin Trials. 2017 Oct;14(5):451-461. doi: 10.1177/1740774517725697. Epub 2017 Aug 22. Clin Trials. 2017. PMID: 28830236 Free PMC article.
Adaptive designs in clinical trials: why use them, and how to run and report them.
Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T. Pallmann P, et al. Among authors: sydes mr. BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7. BMC Med. 2018. PMID: 29490655 Free PMC article.
258 results