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Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial): an open-label, multicentre, randomised, controlled trial.
van Moort I, Preijers T, Bukkems LH, Hazendonk HCAM, van der Bom JG, Laros-van Gorkom BAP, Beckers EAM, Nieuwenhuizen L, van der Meer FJM, Ypma P, Coppens M, Fijnvandraat K, Schutgens REG, Meijer K, Leebeek FWG, Mathôt RAA, Cnossen MH; OPTI-CLOT study group. van Moort I, et al. Among authors: schutgens reg. Lancet Haematol. 2021 Jul;8(7):e492-e502. doi: 10.1016/S2352-3026(21)00135-6. Lancet Haematol. 2021. PMID: 34171280 Clinical Trial.
Factor VIII deficiency does not protect against atherosclerosis.
Biere-Rafi S, Tuinenburg A, Haak BW, Peters M, Huijgen R, De Groot E, Verhamme P, Peerlinck K, Visseren FL, Kruip MJ, Laros-Van Gorkom BA, Gerdes VE, Buller HR, Schutgens RE, Kamphuisen PW. Biere-Rafi S, et al. J Thromb Haemost. 2012 Jan;10(1):30-7. doi: 10.1111/j.1538-7836.2011.04499.x. J Thromb Haemost. 2012. PMID: 21972848 Free article.
Does haemophilia protect against ischaemic cardiovascular disease?
Fransen Van De Putte DE, Fischer K, Schutgens RE, Mauser-Bunschoten EP. Fransen Van De Putte DE, et al. Haemophilia. 2012 Jan;18(1):e35-6. doi: 10.1111/j.1365-2516.2011.02684.x. Epub 2011 Nov 2. Haemophilia. 2012. PMID: 22044761 No abstract available.
Coronary artery calcification in hemophilia A: no evidence for a protective effect of factor VIII deficiency on atherosclerosis.
Tuinenburg A, Rutten A, Kavousi M, Leebeek FW, Ypma PF, Laros-van Gorkom BA, Nijziel MR, Kamphuisen PW, Mauser-Bunschoten EP, Roosendaal G, Biesma DH, van der Lugt A, Hofman A, Witteman JC, Bots ML, Schutgens RE. Tuinenburg A, et al. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):799-804. doi: 10.1161/ATVBAHA.111.238162. Epub 2011 Dec 15. Arterioscler Thromb Vasc Biol. 2012. PMID: 22173226
Von Willebrand factor deficiency and atherosclerosis.
van Galen KP, Tuinenburg A, Smeets EM, Schutgens RE. van Galen KP, et al. Blood Rev. 2012 Sep;26(5):189-96. doi: 10.1016/j.blre.2012.05.002. Epub 2012 Jun 19. Blood Rev. 2012. PMID: 22721874 Review.
Increased prevalence of hypertension in haemophilia patients.
Fransen van de Putte DE, Fischer K, Makris M, Tait RC, Collins PW, Meijer K, Roosendaal G, Chowdary P, Schutgens RE, Mauser-Bunschoten EP. Fransen van de Putte DE, et al. Thromb Haemost. 2012 Oct;108(4):750-5. doi: 10.1160/TH12-05-0313. Epub 2012 Sep 5. Thromb Haemost. 2012. PMID: 22955860
246 results