In vitro model for DNA double-strand break repair analysis in breast cancer reveals cell type-specific associations with age and prognosis.
Deniz M, Kaufmann J, Stahl A, Gundelach T, Janni W, Hoffmann I, Keimling M, Hampp S, Ihle M, Wiesmüller L.
Deniz M, et al.
FASEB J. 2016 Nov;30(11):3786-3799. doi: 10.1096/fj.201600453R. Epub 2016 Aug 5.
FASEB J. 2016.
PMID: 27494941
Our discoveries of altered DSB repair activities in cells may serve as a method to further classify breast cancer to predict responsiveness to adjuvant chemotherapy and/or therapeutics that target DSB repair-dysfunctional tumors.-Deniz, M., Kaufmann, J., Stahl, A., …
Our discoveries of altered DSB repair activities in cells may serve as a method to further classify breast cancer to predict responsiveness …