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Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin.
Dekan Z, Kremsmayr T, Keov P, Godin M, Teakle N, Dürrauer L, Xiang H, Gharib D, Bergmayr C, Hellinger R, Gay M, Vilaseca M, Kurzbach D, Albericio F, Alewood PF, Gruber CW, Muttenthaler M. Dekan Z, et al. Among authors: albericio f. Chem Sci. 2021 Feb 4;12(11):4057-4062. doi: 10.1039/d0sc05501h. Chem Sci. 2021. PMID: 34163676 Free PMC article.
Improving the Gastrointestinal Stability of Linaclotide.
Braga Emidio N, Tran HNT, Andersson A, Dawson PE, Albericio F, Vetter I, Muttenthaler M. Braga Emidio N, et al. Among authors: albericio f. J Med Chem. 2021 Jun 24;64(12):8384-8390. doi: 10.1021/acs.jmedchem.1c00380. Epub 2021 May 12. J Med Chem. 2021. PMID: 33979161 Free PMC article.
Peptide and amide bond-containing dendrimers.
Crespo L, Sanclimens G, Pons M, Giralt E, Royo M, Albericio F. Crespo L, et al. Among authors: albericio f. Chem Rev. 2005 May;105(5):1663-81. doi: 10.1021/cr030449l. Chem Rev. 2005. PMID: 15884786 Review. No abstract available.
Trishomocubane amino acid as a beta-turn scaffold.
Albericio F, Arvidson PI, Bisetty K, Giralt E, Govender T, Jali S, Kongsaeree P, Kruger HG, Prabpai S. Albericio F, et al. Chem Biol Drug Des. 2008 Feb;71(2):125-30. doi: 10.1111/j.1747-0285.2007.00618.x. Epub 2008 Jan 17. Chem Biol Drug Des. 2008. PMID: 18205726
Amino acid-protecting groups.
Isidro-Llobet A, Alvarez M, Albericio F. Isidro-Llobet A, et al. Among authors: albericio f. Chem Rev. 2009 Jun;109(6):2455-504. doi: 10.1021/cr800323s. Chem Rev. 2009. PMID: 19364121 Review. No abstract available.
555 results