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Page 1
Urine APOL1 Isoforms Reflect Plasma-Derived Liver-Synthesized Proteins.
Althage M, Heinrich TM, Miliotis T, Bogstedt A, Ma L, Gautreaux MD, Hicks PJ, Palmer ND, MacPhee I, Hartleib-Geschwindner J, Greasley PJ, Freedman BI. Althage M, et al. Among authors: hartleib geschwindner j. J Am Soc Nephrol. 2021 Oct;32(10):2442-2444. doi: 10.1681/ASN.2021030411. Epub 2021 Jun 23. J Am Soc Nephrol. 2021. PMID: 34162735 Free PMC article. No abstract available.
Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial.
Squire IB, Gabrielsen A, Greasley PJ, Wernevik L, Hartleib-Geschwindner J, Holden J, Johansson S, Rudvik A, Sánchez J, Bamberg K, Melin J, Whittaker A. Squire IB, et al. Among authors: hartleib geschwindner j. Clin Transl Sci. 2022 Oct;15(10):2493-2504. doi: 10.1111/cts.13377. Epub 2022 Aug 20. Clin Transl Sci. 2022. PMID: 35971596 Free PMC article. Clinical Trial.
Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study.
Whittaker A, Kragh ÅM, Hartleib-Geschwindner J, Albayaty M, Backlund A, Greasley PJ, Heijer M, Kjaer M, Forte P, Unwin R, Wernevik L, Ericsson H. Whittaker A, et al. Among authors: hartleib geschwindner j. Clin Transl Sci. 2020 Mar;13(2):275-283. doi: 10.1111/cts.12705. Epub 2019 Oct 30. Clin Transl Sci. 2020. PMID: 31584739 Free PMC article. Clinical Trial.
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator.
Erlandsson F, Albayaty M, Chialda L, Ericsson H, Amilon C, Nelander K, Jansson-Löfmark R, Wernevik L, Kjaer M, Bamberg K, Hartleib-Geschwindner J. Erlandsson F, et al. Among authors: hartleib geschwindner j. Br J Clin Pharmacol. 2018 Jul;84(7):1486-1493. doi: 10.1111/bcp.13562. Epub 2018 Apr 22. Br J Clin Pharmacol. 2018. PMID: 29468715 Free PMC article. Clinical Trial.
The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone.
Bamberg K, William-Olsson L, Johansson U, Jansson-Löfmark R, Hartleib-Geschwindner J. Bamberg K, et al. Among authors: hartleib geschwindner j. J Renin Angiotensin Aldosterone Syst. 2019 Jan-Mar;20(1):1470320319827449. doi: 10.1177/1470320319827449. J Renin Angiotensin Aldosterone Syst. 2019. PMID: 30813831 Free PMC article.
Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
Granberg KL, Yuan ZQ, Lindmark B, Edman K, Kajanus J, Hogner A, Malmgren M, O'Mahony G, Nordqvist A, Lindberg J, Tångefjord S, Kossenjans M, Löfberg C, Brånalt J, Liu D, Selmi N, Nikitidis G, Nordberg P, Hayen A, Aagaard A, Hansson E, Hermansson M, Ivarsson I, Jansson-Löfmark R, Karlsson U, Johansson U, William-Olsson L, Hartleib-Geschwindner J, Bamberg K. Granberg KL, et al. Among authors: hartleib geschwindner j. J Med Chem. 2019 Feb 14;62(3):1385-1406. doi: 10.1021/acs.jmedchem.8b01523. Epub 2019 Jan 30. J Med Chem. 2019. PMID: 30596500
Mineralocorticoid Receptor Antagonism Prevents the Synergistic Effect of Metabolic Challenge and Chronic Kidney Disease on Renal Fibrosis and Inflammation in Mice.
Palacios-Ramirez R, Lima-Posada I, Bonnard B, Genty M, Fernandez-Celis A, Hartleib-Geschwindner J, Foufelle F, Lopez-Andres N, Bamberg K, Jaisser F. Palacios-Ramirez R, et al. Among authors: hartleib geschwindner j. Front Physiol. 2022 Apr 7;13:859812. doi: 10.3389/fphys.2022.859812. eCollection 2022. Front Physiol. 2022. PMID: 35464084 Free PMC article.
Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion.
Bamberg K, Johansson U, Edman K, William-Olsson L, Myhre S, Gunnarsson A, Geschwindner S, Aagaard A, Björnson Granqvist A, Jaisser F, Huang Y, Granberg KL, Jansson-Löfmark R, Hartleib-Geschwindner J. Bamberg K, et al. Among authors: hartleib geschwindner j. PLoS One. 2018 Feb 23;13(2):e0193380. doi: 10.1371/journal.pone.0193380. eCollection 2018. PLoS One. 2018. PMID: 29474466 Free PMC article.
13 results