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The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
Copin R, Baum A, Wloga E, Pascal KE, Giordano S, Fulton BO, Zhou A, Negron N, Lanza K, Chan N, Coppola A, Chiu J, Ni M, Wei Y, Atwal GS, Hernandez AR, Saotome K, Zhou Y, Franklin MC, Hooper AT, McCarthy S, Hamon S, Hamilton JD, Staples HM, Alfson K, Carrion R Jr, Ali S, Norton T, Somersan-Karakaya S, Sivapalasingam S, Herman GA, Weinreich DM, Lipsich L, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. Copin R, et al. Among authors: zhou y, zhou a. Cell. 2021 Jul 22;184(15):3949-3961.e11. doi: 10.1016/j.cell.2021.06.002. Epub 2021 Jun 5. Cell. 2021. PMID: 34161776 Free PMC article. Clinical Trial.
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.
Baum A, Ajithdoss D, Copin R, Zhou A, Lanza K, Negron N, Ni M, Wei Y, Mohammadi K, Musser B, Atwal GS, Oyejide A, Goez-Gazi Y, Dutton J, Clemmons E, Staples HM, Bartley C, Klaffke B, Alfson K, Gazi M, Gonzalez O, Dick E Jr, Carrion R Jr, Pessaint L, Porto M, Cook A, Brown R, Ali V, Greenhouse J, Taylor T, Andersen H, Lewis MG, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. Baum A, et al. Among authors: zhou a. Science. 2020 Nov 27;370(6520):1110-1115. doi: 10.1126/science.abe2402. Epub 2020 Oct 9. Science. 2020. PMID: 33037066 Free PMC article.
Use of Whole-Genome Sequencing to Estimate the Contribution of Immune Evasion and Waning Immunity on Decreasing COVID-19 Vaccine Effectiveness.
Lind ML, Copin R, McCarthy S, Coppi A, Warner F, Ferguson D, Duckwall C, Borg R, Muenker MC, Overton J, Hamon S, Zhou A, Cummings DAT, Ko AI, Hamilton JD, Schulz WL, Hitchings MDT. Lind ML, et al. Among authors: zhou a. J Infect Dis. 2023 Mar 1;227(5):663-674. doi: 10.1093/infdis/jiac453. J Infect Dis. 2023. PMID: 36408616
Proteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues.
Srivastava M, Copin R, Choy A, Zhou A, Olsen O, Wolf S, Shah D, Rye-Weller A, Chen L, Chan N, Coppola A, Lanza K, Negron N, Ni M, Atwal GS, Kyratsous CA, Olson W, Salzler R. Srivastava M, et al. Among authors: zhou a. Front Immunol. 2022 Dec 13;13:1032716. doi: 10.3389/fimmu.2022.1032716. eCollection 2022. Front Immunol. 2022. PMID: 36582233 Free PMC article.
Induced CD8α identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation.
Cubitt CC, Wong P, Dorando HK, Foltz JA, Tran J, Marsala L, Marin ND, Foster M, Schappe T, Fatima H, Becker-Hapak M, Zhou AY, Hwang K, Jacobs MT, Russler-Germain DA, Mace EM, Berrien-Elliott MM, Payton JE, Fehniger TA. Cubitt CC, et al. Among authors: zhou ay. J Clin Invest. 2024 May 28:e173602. doi: 10.1172/JCI173602. Online ahead of print. J Clin Invest. 2024. PMID: 38805302 Free article.
Genome-wide annotation and comparative analysis revealed conserved cuticular protein evolution among non-biting midges with varied environmental adaptability.
Liu W, Zhao K, Zhou A, Wang X, Ge X, Qiao H, Sun X, Yan C, Wang Y. Liu W, et al. Among authors: zhou a. Comp Biochem Physiol Part D Genomics Proteomics. 2024 May 21;51:101248. doi: 10.1016/j.cbd.2024.101248. Online ahead of print. Comp Biochem Physiol Part D Genomics Proteomics. 2024. PMID: 38797005
3,243 results