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Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.
Satoh T, Wang L, Espinosa-Diez C, Wang B, Hahn SA, Noda K, Rochon ER, Dent MR, Levine AR, Baust JJ, Wyman S, Wu YL, Triantafyllou GA, Tang Y, Reynolds M, Shiva S, Hilaire CS, Gomez D, Goncharov DA, Goncharova EA, Chan SY, Straub AC, Lai YC, McTiernan CF, Gladwin MT. Satoh T, et al. Among authors: lai yc. Circulation. 2021 Aug 24;144(8):615-637. doi: 10.1161/CIRCULATIONAHA.121.053889. Epub 2021 Jun 23. Circulation. 2021. PMID: 34157861 Free PMC article.
Pulmonary arterial hypertension: the clinical syndrome.
Lai YC, Potoka KC, Champion HC, Mora AL, Gladwin MT. Lai YC, et al. Circ Res. 2014 Jun 20;115(1):115-30. doi: 10.1161/CIRCRESAHA.115.301146. Circ Res. 2014. PMID: 24951762 Free PMC article. Review.
Novel Targets of Drug Treatment for Pulmonary Hypertension.
Hu J, Xu Q, McTiernan C, Lai YC, Osei-Hwedieh D, Gladwin M. Hu J, et al. Among authors: lai yc. Am J Cardiovasc Drugs. 2015 Aug;15(4):225-34. doi: 10.1007/s40256-015-0125-4. Am J Cardiovasc Drugs. 2015. PMID: 26016608 Review.
SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction.
Lai YC, Tabima DM, Dube JJ, Hughan KS, Vanderpool RR, Goncharov DA, St Croix CM, Garcia-Ocaña A, Goncharova EA, Tofovic SP, Mora AL, Gladwin MT. Lai YC, et al. Circulation. 2016 Feb 23;133(8):717-31. doi: 10.1161/CIRCULATIONAHA.115.018935. Epub 2016 Jan 26. Circulation. 2016. PMID: 26813102 Free PMC article.
Automated Measurement of Blood Vessels in Tissues from Microscopy Images.
Kelly NJ, Dandachi N, Goncharov DA, Pena AZ, Radder JE, Gregory AD, Lai YC, Leme AS, Gladwin MT, Goncharova EA, St Croix CM, Shapiro SD. Kelly NJ, et al. Among authors: lai yc. Curr Protoc Cytom. 2016 Oct 10;78:12.44.1-12.44.13. doi: 10.1002/cpcy.10. Curr Protoc Cytom. 2016. PMID: 27723088 Free PMC article.
Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor.
Kelly NJ, Radder JE, Baust JJ, Burton CL, Lai YC, Potoka KC, Agostini BA, Wood JP, Bachman TN, Vanderpool RR, Dandachi N, Leme AS, Gregory AD, Morris A, Mora AL, Gladwin MT, Shapiro SD. Kelly NJ, et al. Among authors: lai yc. Am J Respir Cell Mol Biol. 2017 Apr;56(4):488-496. doi: 10.1165/rcmb.2016-0176OC. Am J Respir Cell Mol Biol. 2017. PMID: 28085498 Free PMC article.
Development of a Mouse Model of Metabolic Syndrome, Pulmonary Hypertension, and Heart Failure with Preserved Ejection Fraction.
Meng Q, Lai YC, Kelly NJ, Bueno M, Baust JJ, Bachman TN, Goncharov D, Vanderpool RR, Radder JE, Hu J, Goncharova E, Morris AM, Mora AL, Shapiro SD, Gladwin MT. Meng Q, et al. Among authors: lai yc. Am J Respir Cell Mol Biol. 2017 Apr;56(4):497-505. doi: 10.1165/rcmb.2016-0177OC. Am J Respir Cell Mol Biol. 2017. PMID: 28118022 Free PMC article.
Emerging therapeutics in pulmonary hypertension.
Hensley MK, Levine A, Gladwin MT, Lai YC. Hensley MK, et al. Among authors: lai yc. Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L769-L781. doi: 10.1152/ajplung.00259.2017. Epub 2018 Feb 1. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29388467 Free PMC article. Review.
1,262 results