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Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Higuchi Y, Suzuki T, Arimori T, Ikemura N, Mihara E, Kirita Y, Ohgitani E, Mazda O, Motooka D, Nakamura S, Sakai Y, Itoh Y, Sugihara F, Matsuura Y, Matoba S, Okamoto T, Takagi J, Hoshino A. Higuchi Y, et al. Among authors: ikemura n. Nat Commun. 2021 Jun 21;12(1):3802. doi: 10.1038/s41467-021-24013-y. Nat Commun. 2021. PMID: 34155214 Free PMC article.
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.
Ikemura N, Taminishi S, Inaba T, Arimori T, Motooka D, Katoh K, Kirita Y, Higuchi Y, Li S, Suzuki T, Itoh Y, Ozaki Y, Nakamura S, Matoba S, Standley DM, Okamoto T, Takagi J, Hoshino A. Ikemura N, et al. Sci Transl Med. 2022 Jun 22;14(650):eabn7737. doi: 10.1126/scitranslmed.abn7737. Epub 2022 Jun 22. Sci Transl Med. 2022. PMID: 35471044 Free PMC article.
Engineering ACE2 decoy receptors to combat viral escapability.
Arimori T, Ikemura N, Okamoto T, Takagi J, Standley DM, Hoshino A. Arimori T, et al. Among authors: ikemura n. Trends Pharmacol Sci. 2022 Oct;43(10):838-851. doi: 10.1016/j.tips.2022.06.011. Epub 2022 Jul 25. Trends Pharmacol Sci. 2022. PMID: 35902282 Free PMC article. Review.
Angiographic and Clinical Outcomes After Stent-less Coronary Intervention Using Rotational Atherectomy and Drug-Coated Balloon in Patients with De Novo Lesions.
Shiraishi J, Kataoka E, Ozawa T, Shiraga A, Ikemura N, Matsubara Y, Nishimura T, Ito D, Kojima A, Kimura M, Kishita E, Nakagawa Y, Hyogo M, Sawada T. Shiraishi J, et al. Among authors: ikemura n. Cardiovasc Revasc Med. 2020 May;21(5):647-653. doi: 10.1016/j.carrev.2019.08.020. Epub 2019 Aug 28. Cardiovasc Revasc Med. 2020. PMID: 31494063
Generalizable Approach to Quantifying Guideline-Directed Medical Therapy.
Khan MS, Chan PS, Sherrod CF, Ikemura N, Sauer AJ, Jones PG, Fonarow GC, Butler J, DeVore AD, Lund LH, Spertus JA. Khan MS, et al. Among authors: ikemura n. Circ Heart Fail. 2024 May;17(5):e011164. doi: 10.1161/CIRCHEARTFAILURE.123.011164. Epub 2024 May 14. Circ Heart Fail. 2024. PMID: 38742418 Review.
75 results