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Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Higuchi Y, Suzuki T, Arimori T, Ikemura N, Mihara E, Kirita Y, Ohgitani E, Mazda O, Motooka D, Nakamura S, Sakai Y, Itoh Y, Sugihara F, Matsuura Y, Matoba S, Okamoto T, Takagi J, Hoshino A. Higuchi Y, et al. Among authors: hoshino a. Nat Commun. 2021 Jun 21;12(1):3802. doi: 10.1038/s41467-021-24013-y. Nat Commun. 2021. PMID: 34155214 Free PMC article.
p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.
Kimata M, Matoba S, Iwai-Kanai E, Nakamura H, Hoshino A, Nakaoka M, Katamura M, Okawa Y, Mita Y, Okigaki M, Ikeda K, Tatsumi T, Matsubara H. Kimata M, et al. Among authors: hoshino a. Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1908-16. doi: 10.1152/ajpheart.00250.2010. Epub 2010 Oct 8. Am J Physiol Heart Circ Physiol. 2010. PMID: 20935145 Free article.
Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α.
Fukai K, Nakamura A, Hoshino A, Nakanishi N, Okawa Y, Ariyoshi M, Kaimoto S, Uchihashi M, Ono K, Tateishi S, Ikeda K, Ogata T, Ueyama T, Matoba S. Fukai K, et al. Among authors: hoshino a. Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H951-9. doi: 10.1152/ajpheart.00770.2014. Epub 2015 Feb 6. Am J Physiol Heart Circ Physiol. 2015. PMID: 25659487 Free article.
Activation of PPAR-α in the early stage of heart failure maintained myocardial function and energetics in pressure-overload heart failure.
Kaimoto S, Hoshino A, Ariyoshi M, Okawa Y, Tateishi S, Ono K, Uchihashi M, Fukai K, Iwai-Kanai E, Matoba S. Kaimoto S, et al. Among authors: hoshino a. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H305-H313. doi: 10.1152/ajpheart.00553.2016. Epub 2016 Dec 23. Am J Physiol Heart Circ Physiol. 2017. PMID: 28011586 Free article.
Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure.
Uchihashi M, Hoshino A, Okawa Y, Ariyoshi M, Kaimoto S, Tateishi S, Ono K, Yamanaka R, Hato D, Fushimura Y, Honda S, Fukai K, Higuchi Y, Ogata T, Iwai-Kanai E, Matoba S. Uchihashi M, et al. Among authors: hoshino a. Circ Heart Fail. 2017 Dec;10(12):e004417. doi: 10.1161/CIRCHEARTFAILURE.117.004417. Circ Heart Fail. 2017. PMID: 29242353
551 results