Boletta A - Search Results

1

TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease.

Cordido A, Nuñez-Gonzalez L, Martinez-Moreno JM, Lamas-Gonzalez O, Rodriguez-Osorio L, Perez-Gomez MV, Martin-Sanchez D, Outeda P, Chiaravalli M, Watnick T, Boletta A, Diaz C, Carracedo A, Sanz AB, Ortiz A, Garcia-Gonzalez MA. Cordido A, et al. Among authors: boletta a. J Am Soc Nephrol. 2021 Aug;32(8):1913-1932. doi: 10.1681/ASN.2020071094. Epub 2021 Jun 21. J Am Soc Nephrol. 2021. PMID: 34155062 Free PMC article.

2

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

Qian F, Boletta A, Bhunia AK, Xu H, Liu L, Ahrabi AK, Watnick TJ, Zhou F, Germino GG. Qian F, et al. Among authors: boletta a. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16981-6. doi: 10.1073/pnas.252484899. Epub 2002 Dec 13. Proc Natl Acad Sci U S A. 2002. PMID: 12482949 Free PMC article.

3

Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway.

Boca M, Distefano G, Qian F, Bhunia AK, Germino GG, Boletta A. Boca M, et al. Among authors: boletta a. J Am Soc Nephrol. 2006 Mar;17(3):637-47. doi: 10.1681/ASN.2005050534. Epub 2006 Feb 1. J Am Soc Nephrol. 2006. PMID: 16452497 Free PMC article.

4

A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A. Wodarczyk C, et al. Among authors: boletta a. PLoS One. 2009 Sep 23;4(9):e7137. doi: 10.1371/journal.pone.0007137. PLoS One. 2009. PMID: 19774080 Free PMC article.

5

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.

Rowe I, Chiaravalli M, Mannella V, Ulisse V, Quilici G, Pema M, Song XW, Xu H, Mari S, Qian F, Pei Y, Musco G, Boletta A. Rowe I, et al. Among authors: boletta a. Nat Med. 2013 Apr;19(4):488-93. doi: 10.1038/nm.3092. Epub 2013 Mar 24. Nat Med. 2013. PMID: 23524344 Free PMC article.

6

Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.

Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, Carroll T, Boletta A. Castelli M, et al. Among authors: boletta a. Nat Commun. 2013;4:2658. doi: 10.1038/ncomms3658. Nat Commun. 2013. PMID: 24153433 Free PMC article.

7

Defective metabolism in polycystic kidney disease: potential for therapy and open questions.

Rowe I, Boletta A. Rowe I, et al. Among authors: boletta a. Nephrol Dial Transplant. 2014 Aug;29(8):1480-6. doi: 10.1093/ndt/gft521. Epub 2014 Jan 23. Nephrol Dial Transplant. 2014. PMID: 24459136 Review.

8

Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway.

Cebotaru V, Cebotaru L, Kim H, Chiaravalli M, Boletta A, Qian F, Guggino WB. Cebotaru V, et al. Among authors: boletta a. J Biol Chem. 2014 Mar 7;289(10):6404-6414. doi: 10.1074/jbc.M113.501205. Epub 2014 Jan 23. J Biol Chem. 2014. PMID: 24459142 Free PMC article.

9

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures.

Rowe I, Chiaravalli M, Piontek KB, Germino GG, Boletta A. Rowe I, et al. Among authors: boletta a. Biochem Biophys Res Commun. 2014 Feb 21;444(4):473-9. doi: 10.1016/j.bbrc.2014.01.068. Epub 2014 Jan 25. Biochem Biophys Res Commun. 2014. PMID: 24472557 Free PMC article.

10

Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling.

Airik R, Slaats GG, Guo Z, Weiss AC, Khan N, Ghosh A, Hurd TW, Bekker-Jensen S, Schrøder JM, Elledge SJ, Andersen JS, Kispert A, Castelli M, Boletta A, Giles RH, Hildebrandt F. Airik R, et al. Among authors: boletta a. J Am Soc Nephrol. 2014 Nov;25(11):2573-83. doi: 10.1681/ASN.2013050565. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722439 Free PMC article.

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