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Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype.
Polubothu S, Zecchin D, Al-Olabi L, Lionarons DA, Harland M, Horswell S, Thomas AC, Hunt L, Wlodarchak N, Aguilera P, Brand S, Bryant D, Carrera C, Chen H, Elgar G, Harwood CA, Howell M, Larue L, Loughlin S, MacDonald J, Malvehy J, Barberan SM, da Silva VM, Molina M, Morrogh D, Moulding D, Nsengimana J, Pittman A, Puig-Butillé JA, Parmar K, Sebire NJ, Scherer S, Stadnik P, Stanier P, Tell G, Waelchli R, Zarrei M, Puig S, Bataille V, Xing Y, Healy E, Moore GE, Di WL, Newton-Bishop J, Downward J, Kinsler VA. Polubothu S, et al. Genet Med. 2021 Sep;23(9):1636-1647. doi: 10.1038/s41436-021-01204-y. Epub 2021 Jun 18. Genet Med. 2021. PMID: 34145395 Free PMC article.
The genetics of melanoma: the UK experience.
Newton Bishop JA, Harland M, Bishop DT. Newton Bishop JA, et al. Clin Exp Dermatol. 1998 Jul;23(4):158-61. doi: 10.1046/j.1365-2230.1998.00344.x. Clin Exp Dermatol. 1998. PMID: 9894359 Review.
Mutation testing in melanoma families: INK4A, CDK4 and INK4D.
Newton Bishop JA, Harland M, Bennett DC, Bataille V, Goldstein AM, Tucker MA, Ponder BA, Cuzick J, Selby P, Bishop DT. Newton Bishop JA, et al. Br J Cancer. 1999 Apr;80(1-2):295-300. doi: 10.1038/sj.bjc.6690354. Br J Cancer. 1999. PMID: 10390011 Free PMC article.
216 results