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Loss of the long non-coding RNA OIP5-AS1 exacerbates heart failure in a sex-specific manner.
Zhuang A, Calkin AC, Lau S, Kiriazis H, Donner DG, Liu Y, Bond ST, Moody SC, Gould EAM, Colgan TD, Carmona SR, Inouye M, de Aguiar Vallim TQ, Tarling EJ, Quaife-Ryan GA, Hudson JE, Porrello ER, Gregorevic P, Gao XM, Du XJ, McMullen JR, Drew BG. Zhuang A, et al. Among authors: calkin ac. iScience. 2021 May 13;24(6):102537. doi: 10.1016/j.isci.2021.102537. eCollection 2021 Jun 25. iScience. 2021. PMID: 34142046 Free PMC article.
Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes.
Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, Calkin AC, Barit D, Coughlan MT, Drew BG, Lancaster GI, Thomas M, Forbes JM, Nawroth PP, Bierhaus A, Cooper ME, Jandeleit-Dahm KA. Soro-Paavonen A, et al. Among authors: calkin ac. Diabetes. 2008 Sep;57(9):2461-9. doi: 10.2337/db07-1808. Epub 2008 May 28. Diabetes. 2008. PMID: 18511846 Free PMC article.
The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes.
Bond ST, Moody SC, Liu Y, Civelek M, Villanueva CJ, Gregorevic P, Kingwell BA, Hevener AL, Lusis AJ, Henstridge DC, Calkin AC, Drew BG. Bond ST, et al. Among authors: calkin ac. Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E293-E304. doi: 10.1152/ajpendo.00394.2018. Epub 2018 Dec 4. Am J Physiol Endocrinol Metab. 2019. PMID: 30512991 Free PMC article.
An integrative systems genetic analysis of mammalian lipid metabolism.
Parker BL, Calkin AC, Seldin MM, Keating MF, Tarling EJ, Yang P, Moody SC, Liu Y, Zerenturk EJ, Needham EJ, Miller ML, Clifford BL, Morand P, Watt MJ, Meex RCR, Peng KY, Lee R, Jayawardana K, Pan C, Mellett NA, Weir JM, Lazarus R, Lusis AJ, Meikle PJ, James DE, de Aguiar Vallim TQ, Drew BG. Parker BL, et al. Among authors: calkin ac. Nature. 2019 Mar;567(7747):187-193. doi: 10.1038/s41586-019-0984-y. Epub 2019 Feb 27. Nature. 2019. PMID: 30814737 Free PMC article.
Disparate Effects of Diabetes and Hyperlipidemia on Experimental Kidney Disease.
Watson AMD, Gould EAM, Moody SC, Sivakumaran P, Sourris KC, Chow BSM, Koïtka-Weber A, Allen TJ, Jandeleit-Dahm KAM, Cooper ME, Calkin AC. Watson AMD, et al. Among authors: calkin ac. Front Physiol. 2020 Jun 3;11:518. doi: 10.3389/fphys.2020.00518. eCollection 2020. Front Physiol. 2020. PMID: 32581831 Free PMC article.
Tissue-specific expression of Cas9 has no impact on whole-body metabolism in four transgenic mouse lines.
Bond ST, Zhuang A, Yang C, Gould EAM, Sikora T, Liu Y, Fu Y, Watt KI, Tan Y, Kiriazis H, Lancaster GI, Gregorevic P, Henstridge DC, McMullen JR, Meikle PJ, Calkin AC, Drew BG. Bond ST, et al. Among authors: calkin ac. Mol Metab. 2021 Nov;53:101292. doi: 10.1016/j.molmet.2021.101292. Epub 2021 Jul 8. Mol Metab. 2021. PMID: 34246805 Free PMC article.
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