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Identification of ACE2 modifiers by CRISPR screening.
Sherman EJ, Mirabelli C, Tang VT, Khan TG, Kennedy AA, Graham SE, Willer CJ, Tai AW, Sexton JZ, Wobus CE, Emmer BT. Sherman EJ, et al. Among authors: willer cj. bioRxiv [Preprint]. 2021 Jun 10:2021.06.10.447768. doi: 10.1101/2021.06.10.447768. bioRxiv. 2021. PMID: 34127970 Free PMC article. Updated. Preprint.
Genome-scale CRISPR screening for modifiers of cellular LDL uptake.
Emmer BT, Sherman EJ, Lascuna PJ, Graham SE, Willer CJ, Ginsburg D. Emmer BT, et al. Among authors: willer cj. PLoS Genet. 2021 Jan 29;17(1):e1009285. doi: 10.1371/journal.pgen.1009285. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33513160 Free PMC article.
Identification of cell type specific ACE2 modifiers by CRISPR screening.
Sherman EJ, Mirabelli C, Tang VT, Khan TG, Leix K, Kennedy AA, Graham SE, Willer CJ, Tai AW, Sexton JZ, Wobus CE, Emmer BT. Sherman EJ, et al. Among authors: willer cj. PLoS Pathog. 2022 Mar 1;18(3):e1010377. doi: 10.1371/journal.ppat.1010377. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35231079 Free PMC article.
Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans.
Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW. Wang X, et al. Cell Metab. 2021 Feb 2;33(2):350-366.e7. doi: 10.1016/j.cmet.2020.10.020. Epub 2020 Nov 12. Cell Metab. 2021. PMID: 33186557 Free article.
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
Graham SE, Nielsen JB, Zawistowski M, Zhou W, Fritsche LG, Gabrielsen ME, Skogholt AH, Surakka I, Hornsby WE, Fermin D, Larach DB, Kheterpal S, Brummett CM, Lee S, Kang HM, Abecasis GR, Romundstad S, Hallan S, Sampson MG, Hveem K, Willer CJ. Graham SE, et al. Among authors: willer cj. Nat Commun. 2019 Apr 23;10(1):1847. doi: 10.1038/s41467-019-09861-z. Nat Commun. 2019. PMID: 31015462 Free PMC article.
Genome-wide association study of cardiac troponin I in the general population.
Moksnes MR, Røsjø H, Richmond A, Lyngbakken MN, Graham SE, Hansen AF, Wolford BN, Gagliano Taliun SA, LeFaive J, Rasheed H, Thomas LF, Zhou W, Aung N, Surakka I, Douville NJ, Campbell A, Porteous DJ, Petersen SE, Munroe PB, Welsh P, Sattar N, Smith GD, Fritsche LG, Nielsen JB, Åsvold BO, Hveem K, Hayward C, Willer CJ, Brumpton BM, Omland T. Moksnes MR, et al. Among authors: willer cj. Hum Mol Genet. 2021 Oct 13;30(21):2027-2039. doi: 10.1093/hmg/ddab124. Hum Mol Genet. 2021. PMID: 33961016 Free PMC article.
Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2.
Fan Y, Wolford BN, Lu H, Liang W, Sun J, Zhou W, Rom O, Mahajan A, Surakka I, Graham SE, Liu Z, Kim H, Ramdas S, Fritsche LG, Nielsen JB, Gabrielsen ME, Hveem K, Yang D, Song J, Garcia-Barrio MT, Zhang J, Liu W, Zhang K, Willer CJ, Chen YE. Fan Y, et al. Among authors: willer cj. iScience. 2021 Oct 2;24(11):103196. doi: 10.1016/j.isci.2021.103196. eCollection 2021 Nov 19. iScience. 2021. PMID: 34746691 Free PMC article.
Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.
Moksnes MR, Graham SE, Wu KH, Hansen AF, Gagliano Taliun SA, Zhou W, Thorstensen K, Fritsche LG, Gill D, Mason A, Cucca F, Schlessinger D, Abecasis GR, Burgess S, Åsvold BO, Nielsen JB, Hveem K, Willer CJ, Brumpton BM. Moksnes MR, et al. Among authors: willer cj. Commun Biol. 2022 Jun 16;5(1):591. doi: 10.1038/s42003-022-03529-z. Commun Biol. 2022. PMID: 35710628 Free PMC article.
246 results