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Correction: Metal complexes as a promising source for new antibiotics.
Frei A, Zuegg J, Elliott AG, Baker M, Braese S, Brown C, Chen F, Dowson CG, Dujardin G, Jung N, King AP, Mansour AM, Massi M, Moat J, Mohamed HA, Renfrew AK, Rutledge PJ, Sadler PJ, Todd MH, Willans CE, Wilson JJ, Cooper MA, Blaskovich MAT. Frei A, et al. Among authors: dowson cg. Chem Sci. 2020 Apr 16;11(17):4531. doi: 10.1039/d0sc90075c. Chem Sci. 2020. PMID: 34122912 Free PMC article.
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA. Zuegg J, et al. Among authors: dowson cg. Nat Commun. 2015 Jul 21;6:7719. doi: 10.1038/ncomms8719. Nat Commun. 2015. PMID: 26194781 Free PMC article.
Biguanide Iridium(III) Complexes with Potent Antimicrobial Activity.
Chen F, Moat J, McFeely D, Clarkson G, Hands-Portman IJ, Furner-Pardoe JP, Harrison F, Dowson CG, Sadler PJ. Chen F, et al. Among authors: dowson cg. J Med Chem. 2018 Aug 23;61(16):7330-7344. doi: 10.1021/acs.jmedchem.8b00906. Epub 2018 Aug 2. J Med Chem. 2018. PMID: 30070838 Free article.
Structural studies suggest aggregation as one of the modes of action for teixobactin.
Öster C, Walkowiak GP, Hughes DE, Spoering AL, Peoples AJ, Catherwood AC, Tod JA, Lloyd AJ, Herrmann T, Lewis K, Dowson CG, Lewandowski JR. Öster C, et al. Among authors: dowson cg. Chem Sci. 2018 Sep 20;9(47):8850-8859. doi: 10.1039/c8sc03655a. eCollection 2018 Dec 21. Chem Sci. 2018. PMID: 30627403 Free PMC article.
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion.
Kidd SL, Fowler E, Reinhardt T, Compton T, Mateu N, Newman H, Bellini D, Talon R, McLoughlin J, Krojer T, Aimon A, Bradley A, Fairhead M, Brear P, Díaz-Sáez L, McAuley K, Sore HF, Madin A, O'Donovan DH, Huber KVM, Hyvönen M, von Delft F, Dowson CG, Spring DR. Kidd SL, et al. Among authors: dowson cg. Chem Sci. 2020 May 14;11(39):10792-10801. doi: 10.1039/d0sc01232g. Chem Sci. 2020. PMID: 34094333 Free PMC article.
144 results