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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother TR, Tourtellotte WG, Zhang Y, Aleman-Muench GR, Lewis G, Chen W, Kang S, Luevanos M, Trudler D, Lipton SA, Soroosh P, Teijaro J, de la Torre JC, Arditi M, Karin M, Sanchez-Lopez E. Xian H, et al. Among authors: karin m. Immunity. 2021 Jul 13;54(7):1463-1477.e11. doi: 10.1016/j.immuni.2021.05.004. Epub 2021 Jun 10. Immunity. 2021. PMID: 34115964 Free PMC article.
Tumor promotion via injury- and death-induced inflammation.
Kuraishy A, Karin M, Grivennikov SI. Kuraishy A, et al. Among authors: karin m. Immunity. 2011 Oct 28;35(4):467-77. doi: 10.1016/j.immuni.2011.09.006. Immunity. 2011. PMID: 22035839 Free PMC article. Review.
IKKα negatively regulates ASC-dependent inflammasome activation.
Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M, Nuñez G, Dubyak G, Hu Y, Li X. Martin BN, et al. Among authors: karin m. Nat Commun. 2014 Sep 30;5:4977. doi: 10.1038/ncomms5977. Nat Commun. 2014. PMID: 25266676 Free PMC article.
Choline kinase inhibition in rheumatoid arthritis.
Guma M, Sanchez-Lopez E, Lodi A, Garcia-Carbonell R, Tiziani S, Karin M, Lacal JC, Firestein GS. Guma M, et al. Among authors: karin m. Ann Rheum Dis. 2015 Jul;74(7):1399-407. doi: 10.1136/annrheumdis-2014-205696. Epub 2014 Oct 1. Ann Rheum Dis. 2015. PMID: 25274633 Free PMC article.
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.
Shalapour S, Font-Burgada J, Di Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, Willimsky G, Ammirante M, Strasner A, Hansel DE, Jamieson C, Kane CJ, Klatte T, Birner P, Kenner L, Karin M. Shalapour S, et al. Among authors: karin m. Nature. 2015 May 7;521(7550):94-8. doi: 10.1038/nature14395. Epub 2015 Apr 29. Nature. 2015. PMID: 25924065 Free PMC article.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M. Zhong Z, et al. Among authors: karin m. Cell. 2016 Feb 25;164(5):896-910. doi: 10.1016/j.cell.2015.12.057. Cell. 2016. PMID: 26919428 Free PMC article.
720 results