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HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.
Ledneczki I, Horváth A, Tapolcsányi P, Éles J, Molnár KD, Vágó I, Visegrády A, Kiss L, Szigetvári Á, Kóti J, Krámos B, Mahó S, Holm P, Kolok S, Fodor L, Thán M, Kostyalik D, Balázs O, Vastag M, Greiner I, Lévay G, Lendvai B, Némethy Z. Ledneczki I, et al. Among authors: kostyalik d. Eur J Med Chem. 2021 Oct 15;222:113560. doi: 10.1016/j.ejmech.2021.113560. Epub 2021 May 29. Eur J Med Chem. 2021. PMID: 34111828
Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist.
Némethy Z, Kiss B, Lethbridge N, Chazot P, Hajnik T, Tóth A, Détári L, Schmidt É, Czurkó A, Kostyalik D, Oláh V, Hernádi I, Balázs O, Vizi ES, Ledneczki I, Mahó S, Román V, Lendvai B, Lévay G. Némethy Z, et al. Among authors: kostyalik d. Eur J Pharmacol. 2022 Feb 5;916:174621. doi: 10.1016/j.ejphar.2021.174621. Epub 2021 Dec 26. Eur J Pharmacol. 2022. PMID: 34965389
Acute escitalopram treatment inhibits REM sleep rebound and activation of MCH-expressing neurons in the lateral hypothalamus after long term selective REM sleep deprivation.
Kátai Z, Adori C, Kitka T, Vas S, Kalmár L, Kostyalik D, Tóthfalusi L, Palkovits M, Bagdy G. Kátai Z, et al. Among authors: kostyalik d. Psychopharmacology (Berl). 2013 Aug;228(3):439-49. doi: 10.1007/s00213-013-3046-4. Epub 2013 Mar 21. Psychopharmacology (Berl). 2013. PMID: 23515582
12 results