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Dual targeted 2-Benzylideneindanone pendant hydroxamic acid group exhibits selective HDAC6 inhibition along with tubulin stabilization effect.
Kumar K, Das R, Thapa B, Rakhecha B, Srivastava S, Savita K, Israr M, Chanda D, Banerjee D, Shanker K, Bawankule DU, Santini B, Di Paolo ML, Via LD, Passarella D, Negi AS. Kumar K, et al. Among authors: via ld. Bioorg Med Chem. 2023 May 15;86:117300. doi: 10.1016/j.bmc.2023.117300. Epub 2023 Apr 27. Bioorg Med Chem. 2023. PMID: 37146520
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors.
Salerno S, García-Argáez AN, Barresi E, Taliani S, Simorini F, La Motta C, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Via LD. Salerno S, et al. Among authors: via ld. Eur J Med Chem. 2018 Apr 25;150:446-456. doi: 10.1016/j.ejmech.2018.03.013. Epub 2018 Mar 7. Eur J Med Chem. 2018. PMID: 29547832
Targeting multiple G-quadruplex-forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives.
Catalano R, Moraca F, Amato J, Cristofari C, Rigo R, Via LD, Rocca R, Lupia A, Maruca A, Costa G, Catalanotti B, Artese A, Pagano B, Randazzo A, Sissi C, Novellino E, Alcaro S. Catalano R, et al. Among authors: via ld. Eur J Med Chem. 2019 Nov 15;182:111627. doi: 10.1016/j.ejmech.2019.111627. Epub 2019 Aug 16. Eur J Med Chem. 2019. PMID: 31446246
21 results