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Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders.
De Risi M, Tufano M, Alvino FG, Ferraro MG, Torromino G, Gigante Y, Monfregola J, Marrocco E, Pulcrano S, Tunisi L, Lubrano C, Papy-Garcia D, Tuchman Y, Salleo A, Santoro F, Bellenchi GC, Cristino L, Ballabio A, Fraldi A, De Leonibus E. De Risi M, et al. Among authors: papy garcia d. Nat Commun. 2021 Jun 9;12(1):3495. doi: 10.1038/s41467-021-23903-5. Nat Commun. 2021. PMID: 34108486 Free PMC article.
Structure-activity studies of heparan mimetic polyanions for anti-prion therapies.
Ouidja MO, Petit E, Kerros ME, Ikeda Y, Morin C, Carpentier G, Barritault D, Brugère-Picoux J, Deslys JP, Adjou K, Papy-Garcia D. Ouidja MO, et al. Biochem Biophys Res Commun. 2007 Nov 9;363(1):95-100. doi: 10.1016/j.bbrc.2007.08.113. Epub 2007 Aug 29. Biochem Biophys Res Commun. 2007. PMID: 17826736
SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects.
Dubail J, Huber C, Chantepie S, Sonntag S, Tüysüz B, Mihci E, Gordon CT, Steichen-Gersdorf E, Amiel J, Nur B, Stolte-Dijkstra I, van Eerde AM, van Gassen KL, Breugem CC, Stegmann A, Lekszas C, Maroofian R, Karimiani EG, Bruneel A, Seta N, Munnich A, Papy-Garcia D, De La Dure-Molla M, Cormier-Daire V. Dubail J, et al. Nat Commun. 2018 Aug 6;9(1):3087. doi: 10.1038/s41467-018-05191-8. Nat Commun. 2018. PMID: 30082715 Free PMC article.
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.
Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, Mehta A, Wujak L, Cabrera-Fuentes H, Chao CM, Braubach P, Bellusci S, Seeger W, Günther A, Preissner KT, Wygrecka M, Savai R, Papy-Garcia D, Dobreva G, Heikenwalder M, Savai-Pullamsetti S, Braun T, Barreto G. Rubio K, et al. Nat Commun. 2019 May 20;10(1):2229. doi: 10.1038/s41467-019-10066-7. Nat Commun. 2019. PMID: 31110176 Free PMC article.
Heparan sulfate functions are altered in the osteoarthritic cartilage.
Shamdani S, Chantepie S, Flageollet C, Henni-Chebra N, Jouan Y, Eymard F, Hay E, Cohen-Solal M, Papy-Garcia D, Chevalier X, Albanese P. Shamdani S, et al. Arthritis Res Ther. 2020 Dec 7;22(1):283. doi: 10.1186/s13075-020-02352-3. Arthritis Res Ther. 2020. PMID: 33287871 Free PMC article.
Age-related changes in rat myocardium involve altered capacities of glycosaminoglycans to potentiate growth factor functions and heparan sulfate-altered sulfation.
Huynh MB, Morin C, Carpentier G, Garcia-Filipe S, Talhas-Perret S, Barbier-Chassefière V, van Kuppevelt TH, Martelly I, Albanese P, Papy-Garcia D. Huynh MB, et al. J Biol Chem. 2012 Mar 30;287(14):11363-73. doi: 10.1074/jbc.M111.335901. Epub 2012 Feb 1. J Biol Chem. 2012. PMID: 22298772 Free PMC article.
Positioning of nucleosomes containing γ-H2AX precedes active DNA demethylation and transcription initiation.
Dobersch S, Rubio K, Singh I, Günther S, Graumann J, Cordero J, Castillo-Negrete R, Huynh MB, Mehta A, Braubach P, Cabrera-Fuentes H, Bernhagen J, Chao CM, Bellusci S, Günther A, Preissner KT, Kugel S, Dobreva G, Wygrecka M, Braun T, Papy-Garcia D, Barreto G. Dobersch S, et al. Among authors: papy garcia d. Nat Commun. 2021 Feb 16;12(1):1072. doi: 10.1038/s41467-021-21227-y. Nat Commun. 2021. PMID: 33594057 Free PMC article.
80 results