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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation.
Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, Woolf CJ. Huang X, et al. Among authors: lee s. Cell Rep. 2021 Jun 8;35(10):109224. doi: 10.1016/j.celrep.2021.109224. Cell Rep. 2021. PMID: 34107252 Free PMC article.
A three-dimensional human neural cell culture model of Alzheimer's disease.
Choi SH, Kim YH, Hebisch M, Sliwinski C, Lee S, D'Avanzo C, Chen H, Hooli B, Asselin C, Muffat J, Klee JB, Zhang C, Wainger BJ, Peitz M, Kovacs DM, Woolf CJ, Wagner SL, Tanzi RE, Kim DY. Choi SH, et al. Among authors: lee s. Nature. 2014 Nov 13;515(7526):274-8. doi: 10.1038/nature13800. Epub 2014 Oct 12. Nature. 2014. PMID: 25307057 Free PMC article.
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ. Wainger BJ, et al. Among authors: lee s. Nat Neurosci. 2015 Jan;18(1):17-24. doi: 10.1038/nn.3886. Epub 2014 Nov 24. Nat Neurosci. 2015. PMID: 25420066 Free PMC article.
Nociceptor neurons promote IgE class switch in B cells.
Mathur S, Wang JC, Seehus CR, Poirier F, Crosson T, Hsieh YC, Doyle B, Lee S, Woolf CJ, Foster SL, Talbot S. Mathur S, et al. Among authors: lee s. JCI Insight. 2021 Dec 22;6(24):e148510. doi: 10.1172/jci.insight.148510. JCI Insight. 2021. PMID: 34727095 Free PMC article.
Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain.
Alexandre C, Miracca G, Holanda VD, Sharma A, Kourbanova K, Ferreira A, Bicca MA, Zeng X, Nassar VA, Lee S, Kaur S, Sarma SV, Sacré P, Scammell TE, Woolf CJ, Latremoliere A. Alexandre C, et al. Among authors: lee s. Sci Transl Med. 2024 Apr 17;16(743):eadg3036. doi: 10.1126/scitranslmed.adg3036. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630850
Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VK, Bean BP, Levy BD, Woolf CJ. Talbot S, et al. Among authors: lee s. Neuron. 2015 Jul 15;87(2):341-54. doi: 10.1016/j.neuron.2015.06.007. Epub 2015 Jun 25. Neuron. 2015. PMID: 26119026 Free PMC article.
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