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Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.
Motomura H, Ozaki A, Tamori S, Onaga C, Nozaki Y, Waki Y, Takasawa R, Yoshizawa K, Mano Y, Sato T, Sasaki K, Ishiguro H, Miyagi Y, Nagashima Y, Yamamoto K, Sato K, Hanawa T, Tanuma SI, Ohno S, Akimoto K. Motomura H, et al. Among authors: tanuma si. Oncol Lett. 2021 Jul;22(1):547. doi: 10.3892/ol.2021.12808. Epub 2021 May 24. Oncol Lett. 2021. PMID: 34093768 Free PMC article.
Correlation between c-Met and ALDH1 contributes to the survival and tumor-sphere formation of ALDH1 positive breast cancer stem cells and predicts poor clinical outcome in breast cancer.
Nozaki Y, Tamori S, Inada M, Katayama R, Nakane H, Minamishima O, Onodera Y, Abe M, Shiina S, Tamura K, Kodama D, Sato K, Hara Y, Abe R, Takasawa R, Yoshimori A, Shinomiya N, Tanuma SI, Akimoto K. Nozaki Y, et al. Among authors: tanuma si. Genes Cancer. 2017 Jul;8(7-8):628-639. doi: 10.18632/genesandcancer.148. Genes Cancer. 2017. PMID: 28966724 Free PMC article.
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.
Tamori S, Nozaki Y, Motomura H, Nakane H, Katayama R, Onaga C, Kikuchi E, Shimada N, Suzuki Y, Noike M, Hara Y, Sato K, Sato T, Yamamoto K, Hanawa T, Imai M, Abe R, Yoshimori A, Takasawa R, Tanuma SI, Akimoto K. Tamori S, et al. Among authors: tanuma si. Oncotarget. 2018 Nov 23;9(92):36515-36529. doi: 10.18632/oncotarget.26369. eCollection 2018 Nov 23. Oncotarget. 2018. PMID: 30559934 Free PMC article.
GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.
Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K. Motomura H, et al. Among authors: tanuma si. Anticancer Res. 2021 Dec;41(12):5959-5971. doi: 10.21873/anticanres.15415. Anticancer Res. 2021. PMID: 34848450
Piceatannol, a natural trans-stilbene compound, inhibits human glyoxalase I.
Takasawa R, Akahane H, Tanaka H, Shimada N, Yamamoto T, Uchida-Maruki H, Sai M, Yoshimori A, Tanuma SI. Takasawa R, et al. Among authors: tanuma si. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1169-1174. doi: 10.1016/j.bmcl.2017.01.070. Epub 2017 Jan 25. Bioorg Med Chem Lett. 2017. PMID: 28169168
236 results