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Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients.
Matthaei J, Brockmöller J, Steimer W, Pischa K, Leucht S, Kullmann M, Jensen O, Ouethy T, Tzvetkov MV, Rafehi M. Matthaei J, et al. Front Pharmacol. 2021 May 21;12:688950. doi: 10.3389/fphar.2021.688950. eCollection 2021. Front Pharmacol. 2021. PMID: 34093211 Free PMC article.
Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans.
Matthaei J, Bonat WH, Kerb R, Tzvetkov MV, Strube J, Brunke S, Sachse-Seeboth C, Sehrt D, Hofmann U, von Bornemann Hjelmborg J, Schwab M, Brockmöller J. Matthaei J, et al. Front Genet. 2020 Aug 21;11:944. doi: 10.3389/fgene.2020.00944. eCollection 2020. Front Genet. 2020. PMID: 32973880 Free PMC article.
Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1.
Römer S, Meyer MJ, Klein K, Schneider LV, Matthaei J, Tzvetkova A, Łapczuk-Romańska J, Gaedcke J, Droździk M, Brockmöller J, Nies AT, Tzvetkov MV. Römer S, et al. Among authors: matthaei j. Front Pharmacol. 2021 May 7;12:661480. doi: 10.3389/fphar.2021.661480. eCollection 2021. Front Pharmacol. 2021. PMID: 34025422 Free PMC article.
Heritability of metoprolol and torsemide pharmacokinetics.
Matthaei J, Brockmöller J, Tzvetkov MV, Sehrt D, Sachse-Seeboth C, Hjelmborg JB, Möller S, Halekoh U, Hofmann U, Schwab M, Kerb R. Matthaei J, et al. Clin Pharmacol Ther. 2015 Dec;98(6):611-21. doi: 10.1002/cpt.258. Epub 2015 Oct 19. Clin Pharmacol Ther. 2015. PMID: 26344676 Clinical Trial.
33 results