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Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients.
Matthaei J, Brockmöller J, Steimer W, Pischa K, Leucht S, Kullmann M, Jensen O, Ouethy T, Tzvetkov MV, Rafehi M. Matthaei J, et al. Among authors: leucht s. Front Pharmacol. 2021 May 21;12:688950. doi: 10.3389/fphar.2021.688950. eCollection 2021. Front Pharmacol. 2021. PMID: 34093211 Free PMC article.
Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers.
Steimer W, Zöpf K, von Amelunxen S, Pfeiffer H, Bachofer J, Popp J, Messner B, Kissling W, Leucht S. Steimer W, et al. Among authors: leucht s. Clin Chem. 2004 Sep;50(9):1623-33. doi: 10.1373/clinchem.2003.030825. Epub 2004 Jun 17. Clin Chem. 2004. PMID: 15205367
491 results