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Anti-tumour activity of a first-in-class agent NUC-1031 in patients with advanced cancer: results of a phase I study.
Blagden SP, Rizzuto I, Suppiah P, O'Shea D, Patel M, Spiers L, Sukumaran A, Bharwani N, Rockall A, Gabra H, El-Bahrawy M, Wasan H, Leonard R, Habib N, Ghazaly E. Blagden SP, et al. Among authors: ghazaly e. Br J Cancer. 2018 Oct;119(7):815-822. doi: 10.1038/s41416-018-0244-1. Epub 2018 Sep 12. Br J Cancer. 2018. PMID: 30206366 Free PMC article. Clinical Trial.
Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.
Ghazaly EA, Miraki-Moud F, Smith P, Gnanaranjan C, Koniali L, Oke A, Saied MH, Petty R, Matthews J, Stronge R, Joel SP, Young BD, Gribben J, Taussig DC. Ghazaly EA, et al. J Biol Chem. 2020 Apr 17;295(16):5496-5508. doi: 10.1074/jbc.RA119.010467. Epub 2020 Mar 11. J Biol Chem. 2020. PMID: 32161116 Free PMC article.
A Phase Ib Study of NUC-1031 in Combination with Cisplatin for the First-Line Treatment of Patients with Advanced Biliary Tract Cancer (ABC-08).
McNamara MG, Bridgewater J, Palmer DH, Faluyi O, Wasan H, Patel A, Ryder WD, Barber S, Gnanaranjan C, Ghazaly E, Evans TRJ, Valle JW. McNamara MG, et al. Among authors: ghazaly e. Oncologist. 2021 Apr;26(4):e669-e678. doi: 10.1002/onco.13598. Epub 2020 Dec 3. Oncologist. 2021. PMID: 33210382 Free PMC article. Clinical Trial.
[No title available]
[No authors listed] [No authors listed] PMID: 33509590
28 results