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Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes.
Zhang J, Ni Y, Qian L, Fang Q, Zheng T, Zhang M, Gao Q, Zhang Y, Ni J, Hou X, Bao Y, Kovatcheva-Datchary P, Xu A, Li H, Panagiotou G, Jia W. Zhang J, et al. Among authors: kovatcheva datchary p. Adv Sci (Weinh). 2021 Aug;8(16):e2100536. doi: 10.1002/advs.202100536. Epub 2021 Jun 4. Adv Sci (Weinh). 2021. PMID: 34085773 Free PMC article.
Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota.
Li H, Zhang L, Li J, Wu Q, Qian L, He J, Ni Y, Kovatcheva-Datchary P, Yuan R, Liu S, Shen L, Zhang M, Sheng B, Li P, Kang K, Wu L, Fang Q, Long X, Wang X, Li Y, Ye Y, Ye J, Bao Y, Zhao Y, Xu G, Liu X, Panagiotou G, Xu A, Jia W. Li H, et al. Among authors: kovatcheva datchary p. Nat Metab. 2024 Mar;6(3):578-597. doi: 10.1038/s42255-024-00988-y. Epub 2024 Feb 26. Nat Metab. 2024. PMID: 38409604 Free PMC article. Clinical Trial.
The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis.
Fuller M, Priyadarshini M, Gibbons SM, Angueira AR, Brodsky M, Hayes MG, Kovatcheva-Datchary P, Bäckhed F, Gilbert JA, Lowe WL Jr, Layden BT. Fuller M, et al. Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E840-51. doi: 10.1152/ajpendo.00171.2015. Epub 2015 Sep 22. Am J Physiol Endocrinol Metab. 2015. PMID: 26394664 Free PMC article.
FXR is a molecular target for the effects of vertical sleeve gastrectomy.
Ryan KK, Tremaroli V, Clemmensen C, Kovatcheva-Datchary P, Myronovych A, Karns R, Wilson-Pérez HE, Sandoval DA, Kohli R, Bäckhed F, Seeley RJ. Ryan KK, et al. Nature. 2014 May 8;509(7499):183-8. doi: 10.1038/nature13135. Epub 2014 Mar 26. Nature. 2014. PMID: 24670636 Free PMC article.
Intestinal Ralstonia pickettii augments glucose intolerance in obesity.
Udayappan SD, Kovatcheva-Datchary P, Bakker GJ, Havik SR, Herrema H, Cani PD, Bouter KE, Belzer C, Witjes JJ, Vrieze A, de Sonnaville ESV, Chaplin A, van Raalte DH, Aalvink S, Dallinga-Thie GM, Heilig HGHJ, Bergström G, van der Meij S, van Wagensveld BA, Hoekstra JBL, Holleman F, Stroes ESG, Groen AK, Bäckhed F, de Vos WM, Nieuwdorp M. Udayappan SD, et al. PLoS One. 2017 Nov 22;12(11):e0181693. doi: 10.1371/journal.pone.0181693. eCollection 2017. PLoS One. 2017. PMID: 29166392 Free PMC article.
A role for the gut microbiota in energy harvesting?
Tremaroli V, Kovatcheva-Datchary P, Bäckhed F. Tremaroli V, et al. Gut. 2010 Dec;59(12):1589-90. doi: 10.1136/gut.2010.223594. Epub 2010 Oct 12. Gut. 2010. PMID: 20940281 No abstract available.
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