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Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.
J Immunother Cancer. 2021 Jun;9(6):e002181. doi: 10.1136/jitc-2020-002181.
J Immunother Cancer. 2021.
PMID: 34083417
Free PMC article.
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.
Pai CS, Huang JT, Lu X, Simons DM, Park C, Chang A, Tamaki W, Liu E, Roybal KT, Seagal J, Chen M, Hagihara K, Wei XX, DuPage M, Kwek SS, Oh DY, Daud A, Tsai KK, Wu C, Zhang L, Fasso M, Sachidanandam R, Jayaprakash A, Lin I, Casbon AJ, Kinsbury GA, Fong L.
Pai CS, et al.
Immunity. 2019 Feb 19;50(2):477-492.e8. doi: 10.1016/j.immuni.2019.01.006. Epub 2019 Feb 5.
Immunity. 2019.
PMID: 30737146
Free PMC article.
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Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
Sinha M, Zhang L, Subudhi S, Chen B, Marquez J, Liu EV, Allaire K, Cheung A, Ng S, Nguyen C, Friedlander TW, Aggarwal R, Spitzer M, Allison JP, Small EJ, Sharma P, Fong L.
Sinha M, et al. Among authors: liu ev.
J Immunother Cancer. 2021 May;9(5):e002254. doi: 10.1136/jitc-2020-002254.
J Immunother Cancer. 2021.
PMID: 33986125
Free PMC article.
Clinical Trial.
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Modulation of myeloid and T cells in vivo by Bruton's tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma.
Sinha M, Betts C, Zhang L, Griffith MJ, Solman I, Chen B, Liu E, Tamaki W, Stultz J, Marquez J, Sivagnanam S, Cheung A, Pener D, Fahlman A, Taber E, Lerner K, Crocker M, Todd K, Rajagopalan B, Ware C, Bridge M, Vo J, Dragomanovich H, Sudduth-Klinger J, Vaccaro G, Lopez CD, Tempero M, Coussens LM, Fong L.
Sinha M, et al.
J Immunother Cancer. 2023 Jan;11(1):e005425. doi: 10.1136/jitc-2022-005425.
J Immunother Cancer. 2023.
PMID: 36593070
Free PMC article.
Clinical Trial.
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Immune Modulation with RANKL Blockade through Denosumab Treatment in Patients with Cancer.
Chang H, Marquez J, Chen BK, Kim DM, Cheng ML, Liu EV, Yang H, Zhang L, Sinha M, Cheung A, Kwek SS, Chow ED, Bridge M, Aggarwal RR, Friedlander TW, Small EJ, Anderson M, Fong L.
Chang H, et al. Among authors: liu ev.
Cancer Immunol Res. 2024 Apr 2;12(4):453-461. doi: 10.1158/2326-6066.CIR-23-0184.
Cancer Immunol Res. 2024.
PMID: 38276989
Free PMC article.
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Phase II Study of Ipilimumab in Men With Metastatic Prostate Cancer With an Incomplete Response to Androgen Deprivation Therapy.
Graff JN, Stein MN, Surana R, Al Rabadi L, Liu E, Fong L, Bailey S, Latour E, Newby TA, Moran AE, Beer TM.
Graff JN, et al.
Front Oncol. 2020 Aug 7;10:1381. doi: 10.3389/fonc.2020.01381. eCollection 2020.
Front Oncol. 2020.
PMID: 32850444
Free PMC article.
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