Cairns BR - Search Results

1

A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18-SSX Induces Canonical BAF Destruction.

Li J, Mulvihill TS, Li L, Barrott JJ, Nelson ML, Wagner L, Lock IC, Pozner A, Lambert SL, Ozenberger BB, Ward MB, Grossmann AH, Liu T, Banito A, Cairns BR, Jones KB. Li J, et al. Among authors: cairns br. Cancer Discov. 2021 Oct;11(10):2620-2637. doi: 10.1158/2159-8290.CD-20-1219. Epub 2021 Jun 2. Cancer Discov. 2021. PMID: 34078620 Free PMC article.

2

Structure of the RSC complex bound to the nucleosome.

Ye Y, Wu H, Chen K, Clapier CR, Verma N, Zhang W, Deng H, Cairns BR, Gao N, Chen Z. Ye Y, et al. Among authors: cairns br. Science. 2019 Nov 15;366(6467):838-843. doi: 10.1126/science.aay0033. Epub 2019 Oct 31. Science. 2019. PMID: 31672915 Free PMC article.

3

Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A-Mutated Advanced Urothelial Carcinoma.

Gupta S, Albertson DJ, Parnell TJ, Butterfield A, Weston A, Pappas LM, Dalley B, O'Shea JM, Lowrance WT, Cairns BR, Schiffman JD, Sharma S. Gupta S, et al. Among authors: cairns br. Mol Cancer Ther. 2019 Jan;18(1):185-195. doi: 10.1158/1535-7163.MCT-17-0957. Epub 2018 Oct 9. Mol Cancer Ther. 2019. PMID: 30301863 Free PMC article.

4

Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub.

Clapier CR, Verma N, Parnell TJ, Cairns BR. Clapier CR, et al. Among authors: cairns br. Mol Cell. 2020 Nov 19;80(4):712-725.e5. doi: 10.1016/j.molcel.2020.09.024. Epub 2020 Oct 14. Mol Cell. 2020. PMID: 33058778 Free PMC article.

5

Emerging roles for chromatin remodeling in cancer biology.

Cairns BR. Cairns BR. Trends Cell Biol. 2001 Nov;11(11):S15-21. doi: 10.1016/s0962-8924(01)02125-0. Trends Cell Biol. 2001. PMID: 11684437 Review.

6

Antibody detection of translocations in Ewing sarcoma.

Luo W, Milash B, Dalley B, Smith R, Zhou H, Dutrow N, Cairns BR, Lessnick SL. Luo W, et al. Among authors: cairns br. EMBO Mol Med. 2012 Jun;4(6):453-61. doi: 10.1002/emmm.201200225. Epub 2012 Mar 15. EMBO Mol Med. 2012. PMID: 22419563 Free PMC article.

7

Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes.

Schlichter A, Kasten MM, Parnell TJ, Cairns BR. Schlichter A, et al. Among authors: cairns br. Elife. 2020 Jun 4;9:e58130. doi: 10.7554/eLife.58130. Elife. 2020. PMID: 32496195 Free PMC article.

8

p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models.

Grow EJ, Weaver BD, Smith CM, Guo J, Stein P, Shadle SC, Hendrickson PG, Johnson NE, Butterfield RJ, Menafra R, Kloet SL, van der Maarel SM, Williams CJ, Cairns BR. Grow EJ, et al. Among authors: cairns br. Nat Genet. 2021 Aug;53(8):1207-1220. doi: 10.1038/s41588-021-00893-0. Epub 2021 Jul 15. Nat Genet. 2021. PMID: 34267371 Free PMC article.

9

GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia.

Sun W, Guo J, McClellan D, Poeschla A, Bareyan D, Casey MJ, Cairns BR, Tantin D, Engel ME. Sun W, et al. Among authors: cairns br. Mol Cancer Res. 2022 Apr 1;20(4):501-514. doi: 10.1158/1541-7786.MCR-21-0352. Mol Cancer Res. 2022. PMID: 34980595 Free PMC article.

10

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes.

Cakiroglu A, Clapier CR, Ehrensberger AH, Darbo E, Cairns BR, Luscombe NM, Svejstrup JQ. Cakiroglu A, et al. Among authors: cairns br. Genome Res. 2019 Jun;29(6):988-998. doi: 10.1101/gr.243139.118. Epub 2019 May 16. Genome Res. 2019. PMID: 31097474 Free PMC article.

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