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Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon.
de Souza HADS, Escafa VF, Blanco CM, Baptista BO, de Barros JP, Riccio EKP, Rodrigues ABM, Melo GC, Lacerda MVG, de Souza RM, Lima-Junior JDC, Guimarães ACR, da Mota FF, da Silva JHM, Daniel-Ribeiro CT, Pratt-Riccio LR, Totino PRR. de Souza HADS, et al. Among authors: rodrigues abm. Mem Inst Oswaldo Cruz. 2021 May 31;116:e200584. doi: 10.1590/0074-02760200584. eCollection 2021. Mem Inst Oswaldo Cruz. 2021. PMID: 34076074 Free PMC article.
Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles.
Bombaça ACS, Viana PG, Santos ACC, Silva TL, Rodrigues ABM, Guimarães ACR, Goulart MOF, da Silva Júnior EN, Menna-Barreto RFS. Bombaça ACS, et al. Among authors: rodrigues abm. Free Radic Biol Med. 2019 Jan;130:408-418. doi: 10.1016/j.freeradbiomed.2018.11.012. Epub 2018 Nov 14. Free Radic Biol Med. 2019. PMID: 30445126