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Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.
Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM. Tufi R, et al. Among authors: abramov ay. Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19. Nat Cell Biol. 2014. PMID: 24441527 Free PMC article.
Nrf2 regulates ROS production by mitochondria and NADPH oxidase.
Kovac S, Angelova PR, Holmström KM, Zhang Y, Dinkova-Kostova AT, Abramov AY. Kovac S, et al. Among authors: abramov ay. Biochim Biophys Acta. 2015 Apr;1850(4):794-801. doi: 10.1016/j.bbagen.2014.11.021. Epub 2014 Dec 5. Biochim Biophys Acta. 2015. PMID: 25484314 Free PMC article.
205 results