Elwan A - Search Results

1

Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers.

Alsaif NA, Taghour MS, Alanazi MM, Obaidullah AJ, Al-Mehizia AA, Alanazi MM, Aldawas S, Elwan A, Elkady H. Alsaif NA, et al. Among authors: elwan a. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1093-1114. doi: 10.1080/14756366.2021.1915303. J Enzyme Inhib Med Chem. 2021. PMID: 34056992 Free PMC article.

2

Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.

El-Adl K, El-Helby AA, Sakr H, Elwan A. El-Adl K, et al. Among authors: elwan a. Bioorg Chem. 2020 Dec;105:104399. doi: 10.1016/j.bioorg.2020.104399. Epub 2020 Oct 21. Bioorg Chem. 2020. PMID: 33113414

3

Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.

El-Metwally SA, Abou-El-Regal MM, Eissa IH, Mehany ABM, Mahdy HA, Elkady H, Elwan A, Elkaeed EB. El-Metwally SA, et al. Among authors: elwan a. Bioorg Chem. 2021 Jul;112:104947. doi: 10.1016/j.bioorg.2021.104947. Epub 2021 Apr 27. Bioorg Chem. 2021. PMID: 33964580

4

Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.

Alanazi MM, Eissa IH, Alsaif NA, Obaidullah AJ, Alanazi WA, Alasmari AF, Albassam H, Elkady H, Elwan A. Alanazi MM, et al. Among authors: elwan a. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1760-1782. doi: 10.1080/14756366.2021.1956488. J Enzyme Inhib Med Chem. 2021. PMID: 34340610 Free PMC article.

5

Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase.

Alsaif NA, Elwan A, Alanazi MM, Obaidullah AJ, Alanazi WA, Alasmari AF, Albassam H, Mahdy HA, Taghour MS. Alsaif NA, et al. Among authors: elwan a. Mol Divers. 2022 Aug;26(4):1915-1932. doi: 10.1007/s11030-021-10303-6. Epub 2021 Aug 30. Mol Divers. 2022. PMID: 34460053

6

Targeting VEGFR-2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies.

Alsaif NA, Mahdy HA, Alanazi MM, Obaidullah AJ, Alkahtani HM, Al-Hossaini AM, Al-Mehizi AA, Elwan A, Taghour MS. Alsaif NA, et al. Among authors: elwan a. Arch Pharm (Weinheim). 2022 Feb;355(2):e2100359. doi: 10.1002/ardp.202100359. Epub 2021 Dec 3. Arch Pharm (Weinheim). 2022. PMID: 34862634

7

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.

Elkady H, Elwan A, El-Mahdy HA, Doghish AS, Ismail A, Taghour MS, Elkaeed EB, Eissa IH, Dahab MA, Mahdy HA, Khalifa MM. Elkady H, et al. Among authors: elwan a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):397-410. doi: 10.1080/14756366.2021.2015343. J Enzyme Inhib Med Chem. 2022. PMID: 34961427 Free PMC article.

8

Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.

Elwan A, Sakr H, El-Helby AA, El-Morsy A, Abdelgawad MA, Ghoneim MM, El-Sherbiny M, El-Adl K. Elwan A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1556-1567. doi: 10.1080/14756366.2022.2080205. J Enzyme Inhib Med Chem. 2022. PMID: 35635148 Free PMC article.

9

Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers.

Eissa IH, El-Haggar R, Dahab MA, Ahmed MF, Mahdy HA, Alsantali RI, Elwan A, Masurier N, Fatahala SS. Eissa IH, et al. Among authors: elwan a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1587-1599. doi: 10.1080/14756366.2022.2081844. J Enzyme Inhib Med Chem. 2022. PMID: 35637622 Free PMC article.

10

Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.

Yousef RG, Eldehna WM, Elwan A, Abdelaziz AS, Mehany ABM, Gobaara IMM, Alsfouk BA, Elkaeed EB, Metwaly AM, Eissa IH. Yousef RG, et al. Among authors: elwan a. Molecules. 2022 Jun 24;27(13):4079. doi: 10.3390/molecules27134079. Molecules. 2022. PMID: 35807326 Free PMC article.

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