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Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Puxeddu M, Shen H, Bai R, Coluccia A, Bufano M, Nalli M, Sebastiani J, Brancaccio D, Da Pozzo E, Tremolanti C, Martini C, Orlando V, Biagioni S, Sinicropi MS, Ceramella J, Iacopetta D, Coluccia AML, Hamel E, Liu T, Silvestri R, La Regina G. Puxeddu M, et al. Among authors: martini c. Eur J Med Chem. 2021 Oct 5;221:113532. doi: 10.1016/j.ejmech.2021.113532. Epub 2021 May 5. Eur J Med Chem. 2021. PMID: 34052717
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells.
Chelli B, Rossi L, Da Pozzo E, Costa B, Spinetti F, Rechichi M, Salvetti A, Lena A, Simorini F, Vanacore R, Scatena F, Da Settimo F, Gremigni V, Martini C. Chelli B, et al. Among authors: martini c. Chembiochem. 2005 Jun;6(6):1082-8. doi: 10.1002/cbic.200400350. Chembiochem. 2005. PMID: 15883977
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.
Manetti F, Brullo C, Magnani M, Mosci F, Chelli B, Crespan E, Schenone S, Naldini A, Bruno O, Trincavelli ML, Maga G, Carraro F, Martini C, Bondavalli F, Botta M. Manetti F, et al. Among authors: martini c. J Med Chem. 2008 Mar 13;51(5):1252-9. doi: 10.1021/jm701240c. Epub 2008 Feb 8. J Med Chem. 2008. PMID: 18257513
Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis.
Da Settimo F, Simorini F, Taliani S, La Motta C, Marini AM, Salerno S, Bellandi M, Novellino E, Greco G, Cosimelli B, Da Pozzo E, Costa B, Simola N, Morelli M, Martini C. Da Settimo F, et al. Among authors: martini c. J Med Chem. 2008 Sep 25;51(18):5798-806. doi: 10.1021/jm8003224. Epub 2008 Aug 26. J Med Chem. 2008. PMID: 18729350
1,034 results