Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells.
Pan S, Yuan C, Tagmount A, Rudel RA, Ackerman JM, Yaswen P, Vulpe CD, Leitman DC.
Pan S, et al. Among authors: tagmount a.
Environ Health Perspect. 2016 May;124(5):563-9. doi: 10.1289/ehp.1409200. Epub 2015 Oct 27.
Environ Health Perspect. 2016.
PMID: 26502914
Free PMC article.
HRG caused the phosphorylation of serine 167 in ERalpha. BP and HRG produced a synergistic increase in ERalpha recruitment to the c-Myc gene. CONCLUSION: Our results show that HER ligands enhanced the potency of BP to stimulate oncogene expression and breast cancer cell pr …
HRG caused the phosphorylation of serine 167 in ERalpha. BP and HRG produced a synergistic increase in ERalpha recruitment to the c-M …