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Reactive Oxygen Species (ROS)-Responsive Polymersomes with Site-Specific Chemotherapeutic Delivery into Tumors via Spacer Design Chemistry.
Jäger E, Sincari V, Albuquerque LJC, Jäger A, Humajova J, Kucka J, Pankrac J, Paral P, Heizer T, Janouskova O, Konefał R, Pavlova E, Sedlacek O, Giacomelli FC, Pouckova P, Sefc L, Stepanek P, Hruby M. Jäger E, et al. Among authors: humajova j. Biomacromolecules. 2020 Apr 13;21(4):1437-1449. doi: 10.1021/acs.biomac.9b01748. Epub 2020 Mar 4. Biomacromolecules. 2020. PMID: 32083473
pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects.
Albuquerque LJC, Sincari V, Jäger A, Kucka J, Humajova J, Pankrac J, Paral P, Heizer T, Janouškova O, Davidovich I, Talmon Y, Pouckova P, Štěpánek P, Sefc L, Hruby M, Giacomelli FC, Jäger E. Albuquerque LJC, et al. Among authors: humajova j. J Control Release. 2021 Apr 10;332:529-538. doi: 10.1016/j.jconrel.2021.03.013. Epub 2021 Mar 12. J Control Release. 2021. PMID: 33716094
Poly(ethylene oxide monomethyl ether)- block-poly(propylene succinate) Nanoparticles: Synthesis and Characterization, Enzymatic and Cellular Degradation, Micellar Solubilization of Paclitaxel, and in Vitro and in Vivo Evaluation.
Jäger A, Jäger E, Syrová Z, Mazel T, Kováčik L, Raška I, Höcherl A, Kučka J, Konefal R, Humajova J, Poučková P, Štěpánek P, Hrubý M. Jäger A, et al. Among authors: humajova j. Biomacromolecules. 2018 Jul 9;19(7):2443-2458. doi: 10.1021/acs.biomac.8b00048. Epub 2018 Apr 11. Biomacromolecules. 2018. PMID: 29601729
Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies.
Notaro A, Frei A, Rubbiani R, Jakubaszek M, Basu U, Koch S, Mari C, Dotou M, Blacque O, Gouyon J, Bedioui F, Rotthowe N, Winter RF, Goud B, Ferrari S, Tharaud M, Řezáčová M, Humajová J, Tomšík P, Gasser G. Notaro A, et al. Among authors: humajova j. J Med Chem. 2020 May 28;63(10):5568-5584. doi: 10.1021/acs.jmedchem.0c00431. Epub 2020 May 7. J Med Chem. 2020. PMID: 32319768