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Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations.
Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Osana S, Nakagawa T, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M. Mitsuzawa S, et al. Among authors: morimoto s. Stem Cell Reports. 2021 Jun 8;16(6):1527-1541. doi: 10.1016/j.stemcr.2021.04.021. Epub 2021 May 27. Stem Cell Reports. 2021. PMID: 34048688 Free PMC article.
Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M. Akiyama T, et al. Among authors: morimoto s. EBioMedicine. 2019 Jul;45:362-378. doi: 10.1016/j.ebiom.2019.06.013. Epub 2019 Jun 29. EBioMedicine. 2019. PMID: 31262712 Free PMC article.
Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis - Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial).
Morimoto S, Takahashi S, Fukushima K, Saya H, Suzuki N, Aoki M, Okano H, Nakahara J. Morimoto S, et al. Regen Ther. 2019 Jul 26;11:143-166. doi: 10.1016/j.reth.2019.07.002. eCollection 2019 Dec. Regen Ther. 2019. PMID: 31384636 Free PMC article.
[Ropinirole Hydrochloride for ALS].
Takahashi S, Morimoto S, Fukushima K, Nakahara J, Okano H. Takahashi S, et al. Among authors: morimoto s. Brain Nerve. 2019 Nov;71(11):1279-1288. doi: 10.11477/mf.1416201438. Brain Nerve. 2019. PMID: 31722314 Clinical Trial. Japanese.
Ropinirole, a New ALS Drug Candidate Developed Using iPSCs.
Okano H, Yasuda D, Fujimori K, Morimoto S, Takahashi S. Okano H, et al. Among authors: morimoto s. Trends Pharmacol Sci. 2020 Feb;41(2):99-109. doi: 10.1016/j.tips.2019.12.002. Epub 2020 Jan 8. Trends Pharmacol Sci. 2020. PMID: 31926602 Free article. Review.
Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation.
Leventoux N, Morimoto S, Hara K, Nakamura S, Ozawa F, Mitsuzawa S, Akiyama T, Nishiyama A, Suzuki N, Warita H, Aoki M, Okano H. Leventoux N, et al. Among authors: morimoto s. Stem Cell Res. 2020 Jun 28;47:101896. doi: 10.1016/j.scr.2020.101896. Online ahead of print. Stem Cell Res. 2020. PMID: 32659732 Free article.
2,085 results