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Page 1
Methodological considerations for measuring biofluid-based microRNA biomarkers.
Chorley BN, Atabakhsh E, Doran G, Gautier JC, Ellinger-Ziegelbauer H, Jackson D, Sharapova T, Yuen PST, Church RJ, Couttet P, Froetschl R, McDuffie J, Martinez V, Pande P, Peel L, Rafferty C, Simutis FJ, Harrill AH. Chorley BN, et al. Among authors: froetschl r. Crit Rev Toxicol. 2021 Mar;51(3):264-282. doi: 10.1080/10408444.2021.1907530. Epub 2021 May 26. Crit Rev Toxicol. 2021. PMID: 34038674 Free PMC article.
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Corton JC, Mitchell CA, Auerbach S, Bushel P, Ellinger-Ziegelbauer H, Escobar PA, Froetschl R, Harrill AH, Johnson K, Klaunig JE, Pandiri AR, Podtelezhnikov AA, Rager JE, Tanis KQ, van der Laan JW, Vespa A, Yauk CL, Pettit SD, Sistare FD. Corton JC, et al. Among authors: froetschl r. Toxicol Sci. 2022 Jun 28;188(1):4-16. doi: 10.1093/toxsci/kfac041. Toxicol Sci. 2022. PMID: 35404422 Free PMC article.
Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: froetschl r. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
Utility of a next-generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide.
Nicolette J, Luijten M, Sasaki JC, Custer L, Embry M, Froetschl R, Johnson G, Ouedraogo G, Settivari R, Thybaud V, Dearfield KL. Nicolette J, et al. Among authors: froetschl r. Environ Mol Mutagen. 2021 Nov;62(9):512-525. doi: 10.1002/em.22467. Epub 2021 Nov 22. Environ Mol Mutagen. 2021. PMID: 34775645 Free PMC article. Review.
Targets and mechanisms of chemically induced aneuploidy. Part 1 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.
Lynch AM, Eastmond D, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M, Tweats D. Lynch AM, et al. Among authors: froetschl r. Mutat Res Genet Toxicol Environ Mutagen. 2019 Nov;847:403025. doi: 10.1016/j.mrgentox.2019.02.006. Epub 2019 Mar 2. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31699346 Review.
Role of aneuploidy in the carcinogenic process: Part 3 of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.
Tweats D, Eastmond DA, Lynch AM, Elhajouji A, Froetschl R, Kirsch-Volders M, Marchetti F, Masumura K, Pacchierotti F, Schuler M. Tweats D, et al. Among authors: froetschl r. Mutat Res Genet Toxicol Environ Mutagen. 2019 Nov;847:403032. doi: 10.1016/j.mrgentox.2019.03.005. Epub 2019 Mar 29. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31699349 Review.
Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.
Pacchierotti F, Masumura K, Eastmond DA, Elhajouji A, Froetschl R, Kirsch-Volders M, Lynch A, Schuler M, Tweats D, Marchetti F. Pacchierotti F, et al. Among authors: froetschl r. Mutat Res Genet Toxicol Environ Mutagen. 2019 Dec;848:403023. doi: 10.1016/j.mrgentox.2019.02.004. Epub 2019 Mar 20. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31708072
Summary of major conclusions from the 7th International Workshop on Genotoxicity Testing (IWGT), Tokyo, Japan.
Martus HJ, Froetschl R, Gollapudi B, Honma M, Marchetti F, Pfuhler S, Schoeny R, Uno Y, Yauk C, Kirkland DJ. Martus HJ, et al. Among authors: froetschl r. Mutat Res Genet Toxicol Environ Mutagen. 2020 Apr;852:503134. doi: 10.1016/j.mrgentox.2020.503134. Epub 2020 Jan 13. Mutat Res Genet Toxicol Environ Mutagen. 2020. PMID: 32265038 No abstract available.
Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing.
Guérard M, Baum M, Bitsch A, Eisenbrand G, Elhajouji A, Epe B, Habermeyer M, Kaina B, Martus HJ, Pfuhler S, Schmitz C, Sutter A, Thomas AD, Ziemann C, Froetschl R. Guérard M, et al. Among authors: froetschl r. Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:181-201. doi: 10.1016/j.mrrev.2014.11.001. Epub 2014 Nov 11. Mutat Res Rev Mutat Res. 2015. PMID: 25795120 Review.
13 results