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In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR.
Nat Metab. 2021 May;3(5):682-700. doi: 10.1038/s42255-021-00391-x. Epub 2021 May 20.
Nat Metab. 2021.
PMID: 34031592
Free PMC article.
ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced Dedifferentiation.
Ripoche D, Charbord J, Hennino A, Teinturier R, Bonnavion R, Jaafar R, Goehrig D, Cordier-Bussat M, Ritvos O, Zhang CX, Andersson O, Bertolino P.
Ripoche D, et al. Among authors: charbord j.
Mol Cell Biol. 2015 Dec 28;36(5):756-64. doi: 10.1128/MCB.00930-15.
Mol Cell Biol. 2015.
PMID: 26711255
Free PMC article.
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IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation.
Lu J, Liu KC, Schulz N, Karampelias C, Charbord J, Hilding A, Rautio L, Bertolino P, Östenson CG, Brismar K, Andersson O.
Lu J, et al. Among authors: charbord j.
EMBO J. 2016 Sep 15;35(18):2026-44. doi: 10.15252/embj.201592903. Epub 2016 Aug 11.
EMBO J. 2016.
PMID: 27516442
Free PMC article.
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Critical role for adenosine receptor A2a in β-cell proliferation.
Schulz N, Liu KC, Charbord J, Mattsson CL, Tao L, Tworus D, Andersson O.
Schulz N, et al. Among authors: charbord j.
Mol Metab. 2016 Sep 20;5(11):1138-1146. doi: 10.1016/j.molmet.2016.09.006. eCollection 2016 Nov.
Mol Metab. 2016.
PMID: 27818940
Free PMC article.
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In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.
Chu L, Terasaki M, Mattsson CL, Teinturier R, Charbord J, Dirice E, Liu KC, Miskelly MG, Zhou Q, Wierup N, Kulkarni RN, Andersson O.
Chu L, et al. Among authors: charbord j.
Cell Chem Biol. 2022 Sep 15;29(9):1368-1380.e5. doi: 10.1016/j.chembiol.2022.08.001. Epub 2022 Aug 22.
Cell Chem Biol. 2022.
PMID: 35998625
Free PMC article.
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Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis.
Ren L, Charbord J, Chu L, Kemas AM, Bertuzzi M, Mi J, Xing C, Lauschke VM, Andersson O.
Ren L, et al. Among authors: charbord j.
Diabetologia. 2024 Jan;67(1):137-155. doi: 10.1007/s00125-023-06020-4. Epub 2023 Oct 16.
Diabetologia. 2024.
PMID: 37843554
Free PMC article.
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Folate supplementation limits the aggressiveness of glioma via the remethylation of DNA repeats element and genes governing apoptosis and proliferation.
Hervouet E, Debien E, Campion L, Charbord J, Menanteau J, Vallette FM, Cartron PF.
Hervouet E, et al. Among authors: charbord j.
Clin Cancer Res. 2009 May 15;15(10):3519-29. doi: 10.1158/1078-0432.CCR-08-2062.
Clin Cancer Res. 2009.
PMID: 19451595
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High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.
Charbord J, Poydenot P, Bonnefond C, Feyeux M, Casagrande F, Brinon B, Francelle L, Aurégan G, Guillermier M, Cailleret M, Viegas P, Nicoleau C, Martinat C, Brouillet E, Cattaneo E, Peschanski M, Lechuga M, Perrier AL.
Charbord J, et al.
Stem Cells. 2013 Sep;31(9):1816-28. doi: 10.1002/stem.1430.
Stem Cells. 2013.
PMID: 23712629
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