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Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.
Rodina A, Taldone T, Kang Y, Patel PD, Koren J 3rd, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, Erdjument-Bromage H, Hendrickson RC, Cerchietti L, Melnick A, Guzman ML, Chiosis G. Rodina A, et al. Among authors: chiosis g. ACS Chem Biol. 2014 Aug 15;9(8):1698-705. doi: 10.1021/cb500256u. Epub 2014 Jun 17. ACS Chem Biol. 2014. PMID: 24934503 Free PMC article.
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, Caldas-Lopes E, Alpaugh M, Corben A, Riolo M, Beattie B, Pressl C, Peter RI, Xu C, Trondl R, Patel HJ, Shimizu F, Bolaender A, Yang C, Panchal P, Farooq MF, Kishinevsky S, Modi S, Lin O, Chu F, Patil S, Erdjument-Bromage H, Zanzonico P, Hudis C, Studer L, Roboz GJ, Cesarman E, Cerchietti L, Levine R, Melnick A, Larson SM, Lewis JS, Guzman ML, Chiosis G. Rodina A, et al. Among authors: chiosis g. Nature. 2016 Oct 20;538(7625):397-401. doi: 10.1038/nature19807. Epub 2016 Oct 5. Nature. 2016. PMID: 27706135 Free PMC article.
Proteomic interrogation of HSP90 and insights for medical research.
Weidenauer L, Wang T, Joshi S, Chiosis G, Quadroni MR. Weidenauer L, et al. Among authors: chiosis g. Expert Rev Proteomics. 2017 Dec;14(12):1105-1117. doi: 10.1080/14789450.2017.1389649. Epub 2017 Oct 16. Expert Rev Proteomics. 2017. PMID: 28990809 Free PMC article. Review.
Adapting to stress - chaperome networks in cancer.
Joshi S, Wang T, Araujo TLS, Sharma S, Brodsky JL, Chiosis G. Joshi S, et al. Among authors: chiosis g. Nat Rev Cancer. 2018 Sep;18(9):562-575. doi: 10.1038/s41568-018-0020-9. Nat Rev Cancer. 2018. PMID: 29795326 Free PMC article. Review.
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.
Kishinevsky S, Wang T, Rodina A, Chung SY, Xu C, Philip J, Taldone T, Joshi S, Alpaugh ML, Bolaender A, Gutbier S, Sandhu D, Fattahi F, Zimmer B, Shah SK, Chang E, Inda C, Koren J 3rd, Saurat NG, Leist M, Gross SS, Seshan VE, Klein C, Tomishima MJ, Erdjument-Bromage H, Neubert TA, Henrickson RC, Chiosis G, Studer L. Kishinevsky S, et al. Among authors: chiosis g. Nat Commun. 2018 Oct 19;9(1):4345. doi: 10.1038/s41467-018-06486-6. Nat Commun. 2018. PMID: 30341316 Free PMC article.
Chaperome heterogeneity and its implications for cancer study and treatment.
Wang T, Rodina A, Dunphy MP, Corben A, Modi S, Guzman ML, Gewirth DT, Chiosis G. Wang T, et al. Among authors: chiosis g. J Biol Chem. 2019 Feb 8;294(6):2162-2179. doi: 10.1074/jbc.REV118.002811. Epub 2018 Nov 8. J Biol Chem. 2019. PMID: 30409908 Free PMC article. Review.
A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond.
Taldone T, Wang T, Rodina A, Pillarsetty NVK, Digwal CS, Sharma S, Yan P, Joshi S, Pagare PP, Bolaender A, Roboz GJ, Guzman ML, Chiosis G. Taldone T, et al. Among authors: chiosis g. Cold Spring Harb Perspect Biol. 2020 Apr 1;12(4):a034116. doi: 10.1101/cshperspect.a034116. Cold Spring Harb Perspect Biol. 2020. PMID: 30936118 Free PMC article. Review.
171 results