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Page 1
P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis.
Santiago-Carvalho I, de Almeida-Santos G, Bomfim CCB, de Souza PC, Silva JCSE, de Melo BMS, Amaral EP, Cione MVP, Lasunskaia E, Hirata MH, Alves-Filho JCF, Nakaya HI, Alvarez JM, D'Império Lima MR. Santiago-Carvalho I, et al. Among authors: hirata mh. Front Cell Infect Microbiol. 2021 May 5;11:672472. doi: 10.3389/fcimb.2021.672472. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34026666 Free PMC article.
Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Amaral EP, et al. Among authors: hirata mh. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 24991816 Free PMC article.
Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis.
Nascimento IP, Rodriguez D, Santos CC, Amaral EP, Rofatto HK, Junqueira-Kipnis AP, Gonçalves EDC, D'Império-Lima MR, Hirata MH, Silva CL, Winter N, Gicquel B, Mills KHG, Pizza M, Rappuoli R, Leite LCC. Nascimento IP, et al. Among authors: hirata mh. Sci Rep. 2017 May 18;7(1):2109. doi: 10.1038/s41598-017-02003-9. Sci Rep. 2017. PMID: 28522873 Free PMC article.
T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections.
Santiago-Carvalho I, Almeida-Santos G, Macedo BG, Barbosa-Bomfim CC, Almeida FM, Pinheiro Cione MV, Vardam-Kaur T, Masuda M, Van Dijk S, Melo BM, Silva do Nascimento R, da Conceição Souza R, Peixoto-Rangel AL, Coutinho-Silva R, Hirata MH, Alves-Filho JC, Álvarez JM, Lassounskaia E, Borges da Silva H, D'Império-Lima MR. Santiago-Carvalho I, et al. Among authors: hirata mh. Cell Rep. 2023 Nov 28;42(11):113448. doi: 10.1016/j.celrep.2023.113448. Epub 2023 Nov 15. Cell Rep. 2023. PMID: 37967010 Free PMC article.
MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil.
Castelli EC, de Castro MV, Naslavsky MS, Scliar MO, Silva NSB, Pereira RN, Ciriaco VAO, Castro CFB, Mendes-Junior CT, Silveira ES, de Oliveira IM, Antonio EC, Vieira GF, Meyer D, Nunes K, Matos LRB, Silva MVR, Wang JYT, Esposito J, Cória VR, Magawa JY, Santos KS, Cunha-Neto E, Kalil J, Bortolin RH, Hirata MH, Dell'Aquila LP, Razuk-Filho A, Batista-Júnior PB, Duarte-Neto AN, Dolhnikoff M, Saldiva PHN, Passos-Bueno MR, Zatz M. Castelli EC, et al. Among authors: hirata mh. Front Immunol. 2022 Oct 25;13:975918. doi: 10.3389/fimmu.2022.975918. eCollection 2022. Front Immunol. 2022. PMID: 36389712 Free PMC article.
Interferome signature dynamics during the anti-dengue immune response: a systems biology characterization.
Usuda JN, Plaça DR, Fonseca DLM, Marques AHC, Filgueiras IS, Chaves VGB, Adri AS, Torrentes-Carvalho A, Hirata MH, Freire PP, Catar R, Cabral-Miranda G, Schimke LF, Moll G, Cabral-Marques O. Usuda JN, et al. Among authors: hirata mh. Front Immunol. 2023 Aug 10;14:1243516. doi: 10.3389/fimmu.2023.1243516. eCollection 2023. Front Immunol. 2023. PMID: 37638052 Free PMC article.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Dagli-Hernandez C, Ferreira GM, Freitas RCC, Borges JB, Oliveira VF, Gonçalves RM, Faludi AA, Marçal EDSR, Bastos GM, Bortolin RH, Hirata MH, Hirata RDC. Dagli-Hernandez C, et al. Among authors: hirata mh. Pharmacogenet Genomics. 2024 Jun 1;34(4):91-104. doi: 10.1097/FPC.0000000000000524. Epub 2024 Feb 7. Pharmacogenet Genomics. 2024. PMID: 38682317
259 results