Gupta M - Search Results

1

Safranal inhibits NLRP3 inflammasome activation by preventing ASC oligomerization.

Gupta M, Wani A, Ahsan AU, Ali M, Chibber P, Singh S, Digra SK, Datt M, Bharate SB, Vishwakarma RA, Singh G, Kumar A. Gupta M, et al. Toxicol Appl Pharmacol. 2021 Jul 15;423:115582. doi: 10.1016/j.taap.2021.115582. Epub 2021 May 18. Toxicol Appl Pharmacol. 2021. PMID: 34019860

2

Soluble Aβ_1-42 suppresses TNF-α and activates NLRP3 inflammasome in THP-1 macrophages.

Gupta M, Wani A, Ul Ahsan A, Chopra M, Vishwakarma RA, Singh G, Kumar A. Gupta M, et al. Cytokine. 2018 Nov;111:84-87. doi: 10.1016/j.cyto.2018.07.026. Epub 2018 Aug 17. Cytokine. 2018. PMID: 30125779

3

IIIM-941, a Stilbene Derivative Inhibits NLRP3 Inflammasome Activation by Inducing Autophagy.

Ali M, Gupta M, Wani A, Sharma A, Abdullaha M, Kour D, Choudhary S, Bharate SB, Singh G, Kumar A. Ali M, et al. Among authors: gupta m. Front Pharmacol. 2021 Jun 25;12:695712. doi: 10.3389/fphar.2021.695712. eCollection 2021. Front Pharmacol. 2021. PMID: 34248643 Free PMC article.

4

(Z)-2-(3-Chlorobenzylidene)-3,4-dihydro-N-(2-methoxyethyl)-3-oxo-2H-benzo[b][1,4]oxazine-6-carboxamide as GSK-3β inhibitor: Identification by virtual screening and its validation in enzyme- and cell-based assay.

Joshi P, Gupta M, Vishwakarma RA, Kumar A, Bharate SB. Joshi P, et al. Among authors: gupta m. Chem Biol Drug Des. 2017 Jun;89(6):964-971. doi: 10.1111/cbdd.12913. Epub 2017 Feb 16. Chem Biol Drug Des. 2017. PMID: 27896926

5

Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway.

Wani A, Gupta M, Ahmad M, Shah AM, Ahsan AU, Qazi PH, Malik F, Singh G, Sharma PR, Kaddoumi A, Bharate SB, Vishwakarma RA, Kumar A. Wani A, et al. Among authors: gupta m. Autophagy. 2019 Oct;15(10):1810-1828. doi: 10.1080/15548627.2019.1596476. Epub 2019 Apr 2. Autophagy. 2019. PMID: 30894052 Free PMC article.

6

Discovery and preclinical development of IIIM-160, a Bergenia ciliata-based anti-inflammatory and anti-arthritic botanical drug candidate.

Bharate SB, Kumar V, Bharate SS, Singh B, Singh G, Singh A, Gupta M, Singh D, Kumar A, Singh S, Vishwakarma RA. Bharate SB, et al. Among authors: gupta m. J Integr Med. 2019 May;17(3):192-204. doi: 10.1016/j.joim.2019.03.001. Epub 2019 Mar 6. J Integr Med. 2019. PMID: 30898582

7

Preclinical Development of Crocus sativus-Based Botanical Lead IIIM-141 for Alzheimer's Disease: Chemical Standardization, Efficacy, Formulation Development, Pharmacokinetics, and Safety Pharmacology.

Bharate SS, Kumar V, Singh G, Singh A, Gupta M, Singh D, Kumar A, Vishwakarma RA, Bharate SB. Bharate SS, et al. Among authors: gupta m. ACS Omega. 2018 Aug 20;3(8):9572-9585. doi: 10.1021/acsomega.8b00841. eCollection 2018 Aug 31. ACS Omega. 2018. PMID: 31459089 Free PMC article.

8

Evaluation of rohitukine-enriched fraction of Dysoxylum binectariferum Hook.f. (leaves) as anti-arthritic phytopharmaceutical candidate: Chemical standardization, in-vivo validation, formulation development and oral pharmacokinetics.

Kumar V, Bharate SS, Bhurta D, Gupta M, Gandhi SG, Singh D, Jaglan S, Kumar A, Vishwakarma RA, Bharate SB. Kumar V, et al. Among authors: gupta m. J Ethnopharmacol. 2020 May 23;254:112758. doi: 10.1016/j.jep.2020.112758. Epub 2020 Mar 9. J Ethnopharmacol. 2020. PMID: 32165175

9

Long-circulatory nanoparticles for gemcitabine delivery: Development and investigation of pharmacokinetics and in-vivo anticancer efficacy.

Khare V, Singh A, Mahajan G, Alam N, Kour S, Gupta M, Kumar A, Singh G, Singh SK, Saxena AK, Mondhe DM, Gupta PN. Khare V, et al. Among authors: gupta m, gupta pn. Eur J Pharm Sci. 2016 Sep 20;92:183-93. doi: 10.1016/j.ejps.2016.07.007. Epub 2016 Jul 9. Eur J Pharm Sci. 2016. PMID: 27404580

10

Indolyl-isoxazolidines attenuate LPS-stimulated pro-inflammatory cytokines and increase survival in a mouse model of sepsis: Identification of potent lead.

Singh G, Singh G, Bhatti R, Gupta M, Kumar A, Sharma A, Singh Ishar MP. Singh G, et al. Among authors: gupta m. Eur J Med Chem. 2018 Jun 10;153:56-64. doi: 10.1016/j.ejmech.2018.04.004. Epub 2018 Apr 3. Eur J Med Chem. 2018. PMID: 29656890

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