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Chiral Pharmacokinetics and Metabolite Profile of Prolonged-release Ketamine Tablets in Healthy Human Subjects.
Anesthesiology. 2021 Aug 1;135(2):326-339. doi: 10.1097/ALN.0000000000003829.
Anesthesiology. 2021.
PMID: 34019627
Free article.
Effects of the P-Glycoprotein Inhibitor Clarithromycin on the Pharmacokinetics of Intravenous and Oral Trospium Chloride: A 4-Way Crossover Drug-Drug Interaction Study in Healthy Subjects.
Abebe BT, Weiss M, Modess C, Roustom T, Tadken T, Wegner D, Schwantes U, Neumeister C, Schulz HU, Scheuch E, Siegmund W.
Abebe BT, et al. Among authors: roustom t.
J Clin Pharmacol. 2019 Oct;59(10):1319-1330. doi: 10.1002/jcph.1421. Epub 2019 Apr 11.
J Clin Pharmacol. 2019.
PMID: 30973998
Clinical Trial.
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Trospium chloride is absorbed from two intestinal "absorption windows" with different permeability in healthy subjects.
Tadken T, Weiss M, Modess C, Wegner D, Roustom T, Neumeister C, Schwantes U, Schulz HU, Weitschies W, Siegmund W.
Tadken T, et al. Among authors: roustom t.
Int J Pharm. 2016 Dec 30;515(1-2):367-373. doi: 10.1016/j.ijpharm.2016.10.030. Epub 2016 Oct 17.
Int J Pharm. 2016.
PMID: 27765726
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Resolving the physiological conditions in bioavailability and bioequivalence studies: Comparison of fasted and fed state.
Schneider F, Grimm M, Koziolek M, Modeß C, Dokter A, Roustom T, Siegmund W, Weitschies W.
Schneider F, et al. Among authors: roustom t.
Eur J Pharm Biopharm. 2016 Nov;108:214-219. doi: 10.1016/j.ejpb.2016.09.009. Epub 2016 Sep 14.
Eur J Pharm Biopharm. 2016.
PMID: 27639346
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Intragastric pH and pressure profiles after intake of the high-caloric, high-fat meal as used for food effect studies.
Koziolek M, Schneider F, Grimm M, Modeβ C, Seekamp A, Roustom T, Siegmund W, Weitschies W.
Koziolek M, et al. Among authors: roustom t.
J Control Release. 2015 Dec 28;220(Pt A):71-78. doi: 10.1016/j.jconrel.2015.10.022. Epub 2015 Oct 22.
J Control Release. 2015.
PMID: 26476174
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