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An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities.
O'Sullivan DM, Doyle RM, Temisak S, Redshaw N, Whale AS, Logan G, Huang J, Fischer N, Amos GCA, Preston MD, Marchesi JR, Wagner J, Parkhill J, Motro Y, Denise H, Finn RD, Harris KA, Kay GL, O'Grady J, Ransom-Jones E, Wu H, Laing E, Studholme DJ, Benavente ED, Phelan J, Clark TG, Moran-Gilad J, Huggett JF. O'Sullivan DM, et al. Sci Rep. 2021 May 19;11(1):10590. doi: 10.1038/s41598-021-89881-2. Sci Rep. 2021. PMID: 34012005 Free PMC article.
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing.
Clark TG, Mallard K, Coll F, Preston M, Assefa S, Harris D, Ogwang S, Mumbowa F, Kirenga B, O'Sullivan DM, Okwera A, Eisenach KD, Joloba M, Bentley SD, Ellner JJ, Parkhill J, Jones-López EC, McNerney R. Clark TG, et al. PLoS One. 2013 Dec 11;8(12):e83012. doi: 10.1371/journal.pone.0083012. eCollection 2013. PLoS One. 2013. PMID: 24349420 Free PMC article. Clinical Trial.
The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis.
Devonshire AS, O'Sullivan DM, Honeyborne I, Jones G, Karczmarczyk M, Pavšič J, Gutteridge A, Milavec M, Mendoza P, Schimmel H, Van Heuverswyn F, Gorton R, Cirillo DM, Borroni E, Harris K, Barnard M, Heydenrych A, Ndusilo N, Wallis CL, Pillay K, Barry T, Reddington K, Richter E, Mozioğlu E, Akyürek S, Yalçınkaya B, Akgoz M, Žel J, Foy CA, McHugh TD, Huggett JF. Devonshire AS, et al. BMC Infect Dis. 2016 Aug 3;16:366. doi: 10.1186/s12879-016-1696-7. BMC Infect Dis. 2016. PMID: 27487852 Free PMC article.
Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine.
Whale AS, Jones GM, Pavšič J, Dreo T, Redshaw N, Akyürek S, Akgöz M, Divieto C, Sassi MP, He HJ, Cole KD, Bae YK, Park SR, Deprez L, Corbisier P, Garrigou S, Taly V, Larios R, Cowen S, O'Sullivan DM, Bushell CA, Goenaga-Infante H, Foy CA, Woolford AJ, Parkes H, Huggett JF, Devonshire AS. Whale AS, et al. Clin Chem. 2018 Sep;64(9):1296-1307. doi: 10.1373/clinchem.2017.285478. Epub 2018 Jun 14. Clin Chem. 2018. PMID: 29903874
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study.
Doyle RM, O'Sullivan DM, Aller SD, Bruchmann S, Clark T, Coello Pelegrin A, Cormican M, Diez Benavente E, Ellington MJ, McGrath E, Motro Y, Phuong Thuy Nguyen T, Phelan J, Shaw LP, Stabler RA, van Belkum A, van Dorp L, Woodford N, Moran-Gilad J, Huggett JF, Harris KA. Doyle RM, et al. Microb Genom. 2020 Feb;6(2):e000335. doi: 10.1099/mgen.0.000335. Epub 2020 Feb 12. Microb Genom. 2020. PMID: 32048983 Free PMC article.
STROBE-metagenomics: a STROBE extension statement to guide the reporting of metagenomics studies.
Bharucha T, Oeser C, Balloux F, Brown JR, Carbo EC, Charlett A, Chiu CY, Claas ECJ, de Goffau MC, de Vries JJC, Eloit M, Hopkins S, Huggett JF, MacCannell D, Morfopoulou S, Nath A, O'Sullivan DM, Reoma LB, Shaw LP, Sidorov I, Simner PJ, Van Tan L, Thomson EC, van Dorp L, Wilson MR, Breuer J, Field N. Bharucha T, et al. Lancet Infect Dis. 2020 Oct;20(10):e251-e260. doi: 10.1016/S1473-3099(20)30199-7. Epub 2020 Aug 5. Lancet Infect Dis. 2020. PMID: 32768390 Free PMC article. Review.
258 results