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Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression.
Wiese BM, Liktor-Busa E, Levine A, Couture SA, Nikas SP, Ji L, Liu Y, Mackie K, Makriyannis A, Largent-Milnes TM, Vanderah TW. Wiese BM, et al. Among authors: mackie k. Cannabis Cannabinoid Res. 2021 Oct;6(5):401-412. doi: 10.1089/can.2020.0076. Epub 2020 Nov 13. Cannabis Cannabinoid Res. 2021. PMID: 33998869 Free PMC article.
Identification and functional characterization of brainstem cannabinoid CB2 receptors.
Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA. Van Sickle MD, et al. Among authors: mackie k. Science. 2005 Oct 14;310(5746):329-32. doi: 10.1126/science.1115740. Science. 2005. PMID: 16224028
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice.
Bashashati M, Storr MA, Nikas SP, Wood JT, Godlewski G, Liu J, Ho W, Keenan CM, Zhang H, Alapafuja SO, Cravatt BF, Lutz B, Mackie K, Kunos G, Patel KD, Makriyannis A, Davison JS, Sharkey KA. Bashashati M, et al. Among authors: mackie k. Br J Pharmacol. 2012 Mar;165(5):1556-71. doi: 10.1111/j.1476-5381.2011.01644.x. Br J Pharmacol. 2012. PMID: 21883147 Free PMC article.
AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally restricted manner.
Keenan CM, Storr MA, Thakur GA, Wood JT, Wager-Miller J, Straiker A, Eno MR, Nikas SP, Bashashati M, Hu H, Mackie K, Makriyannis A, Sharkey KA. Keenan CM, et al. Among authors: mackie k. Br J Pharmacol. 2015 May;172(9):2406-18. doi: 10.1111/bph.13069. Epub 2015 Feb 27. Br J Pharmacol. 2015. PMID: 25572435 Free PMC article.
Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
Janero DR, Yaddanapudi S, Zvonok N, Subramanian KV, Shukla VG, Stahl E, Zhou L, Hurst D, Wager-Miller J, Bohn LM, Reggio PH, Mackie K, Makriyannis A. Janero DR, et al. Among authors: mackie k. ACS Chem Neurosci. 2015 Aug 19;6(8):1400-10. doi: 10.1021/acschemneuro.5b00090. Epub 2015 May 29. ACS Chem Neurosci. 2015. PMID: 25978068 Free PMC article.
Chronic Adolescent Δ9-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment.
Murphy M, Mills S, Winstone J, Leishman E, Wager-Miller J, Bradshaw H, Mackie K. Murphy M, et al. Among authors: mackie k. Cannabis Cannabinoid Res. 2017 Sep 1;2(1):235-246. doi: 10.1089/can.2017.0034. eCollection 2017. Cannabis Cannabinoid Res. 2017. PMID: 29098186 Free PMC article.
465 results