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Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Xiao L, Somers K, Murray J, Pandher R, Karsa M, Ronca E, Bongers A, Terry R, Ehteda A, Gamble LD, Issaeva N, Leonova KI, O'Connor A, Mayoh C, Venkat P, Quek H, Brand J, Kusuma FK, Pettitt JA, Mosmann E, Kearns A, Eden G, Alfred S, Allan S, Zhai L, Kamili A, Gifford AJ, Carter DR, Henderson MJ, Fletcher JI, Marshall G, Johnstone RW, Cesare AJ, Ziegler DS, Gudkov AV, Gurova KV, Norris MD, Haber M. Xiao L, et al. Among authors: johnstone rw. Clin Cancer Res. 2021 Aug 1;27(15):4338-4352. doi: 10.1158/1078-0432.CCR-20-2357. Epub 2021 May 16. Clin Cancer Res. 2021. PMID: 33994371 Free PMC article.
Anticancer activities of histone deacetylase inhibitors.
Bolden JE, Peart MJ, Johnstone RW. Bolden JE, et al. Among authors: johnstone rw. Nat Rev Drug Discov. 2006 Sep;5(9):769-84. doi: 10.1038/nrd2133. Nat Rev Drug Discov. 2006. PMID: 16955068 Review.
Histone deacetylase inhibitors in cancer therapy.
Rasheed WK, Johnstone RW, Prince HM. Rasheed WK, et al. Among authors: johnstone rw. Expert Opin Investig Drugs. 2007 May;16(5):659-78. doi: 10.1517/13543784.16.5.659. Expert Opin Investig Drugs. 2007. PMID: 17461739 Review.
Histone deacetylase inhibitors in lymphoma and solid malignancies.
Rasheed W, Bishton M, Johnstone RW, Prince HM. Rasheed W, et al. Among authors: johnstone rw. Expert Rev Anticancer Ther. 2008 Mar;8(3):413-32. doi: 10.1586/14737140.8.3.413. Expert Rev Anticancer Ther. 2008. PMID: 18366289 Review.
Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma.
Ellis L, Pan Y, Smyth GK, George DJ, McCormack C, Williams-Truax R, Mita M, Beck J, Burris H, Ryan G, Atadja P, Butterfoss D, Dugan M, Culver K, Johnstone RW, Prince HM. Ellis L, et al. Among authors: johnstone rw. Clin Cancer Res. 2008 Jul 15;14(14):4500-10. doi: 10.1158/1078-0432.CCR-07-4262. Clin Cancer Res. 2008. PMID: 18628465 Clinical Trial.
286 results