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HOXC10 Suppresses Browning to Maintain White Adipocyte Identity.
Diabetes. 2021 Aug;70(8):1654-1663. doi: 10.2337/db21-0114. Epub 2021 May 14.
Diabetes. 2021.
PMID: 33990396
Free PMC article.
Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation.
Sim MFM, Persiani E, Talukder MMU, Mcilroy GD, Roumane A, Edwardson JM, Rochford JJ.
Sim MFM, et al.
Sci Rep. 2020 Feb 24;10(1):3259. doi: 10.1038/s41598-020-59982-5.
Sci Rep. 2020.
PMID: 32094408
Free PMC article.
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Discovering metabolic disease gene interactions by correlated effects on cellular morphology.
Jiao Y, Ahmed U, Sim MFM, Bejar A, Zhang X, Talukder MMU, Rice R, Flannick J, Podgornaia AI, Reilly DF, Engreitz JM, Kost-Alimova M, Hartland K, Mercader JM, Georges S, Wagh V, Tadin-Strapps M, Doench JG, Edwardson JM, Rochford JJ, Rosen ED, Majithia AR.
Jiao Y, et al. Among authors: sim mfm.
Mol Metab. 2019 Jun;24:108-119. doi: 10.1016/j.molmet.2019.03.001. Epub 2019 Mar 13.
Mol Metab. 2019.
PMID: 30940487
Free PMC article.
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Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Larder R, Sim MFM, Gulati P, Antrobus R, Tung YCL, Rimmington D, Ayuso E, Polex-Wolf J, Lam BYH, Dias C, Logan DW, Virtue S, Bosch F, Yeo GSH, Saudek V, O'Rahilly S, Coll AP.
Larder R, et al. Among authors: sim mfm.
Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9421-9426. doi: 10.1073/pnas.1707310114. Epub 2017 Aug 15.
Proc Natl Acad Sci U S A. 2017.
PMID: 28811369
Free PMC article.
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Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis.
Talukder MM, Sim MF, O'Rahilly S, Edwardson JM, Rochford JJ.
Talukder MM, et al.
Mol Metab. 2015 Jan 6;4(3):199-209. doi: 10.1016/j.molmet.2014.12.013. eCollection 2015 Mar.
Mol Metab. 2015.
PMID: 25737955
Free PMC article.
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Analyzing the functions and structure of the human lipodystrophy protein seipin.
Sim MF, Talukder MU, Dennis RJ, Edwardson JM, Rochford JJ.
Sim MF, et al.
Methods Enzymol. 2014;537:161-75. doi: 10.1016/B978-0-12-411619-1.00009-4.
Methods Enzymol. 2014.
PMID: 24480346
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Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms.
Sim MF, Talukder MM, Dennis RJ, O'Rahilly S, Edwardson JM, Rochford JJ.
Sim MF, et al.
Diabetologia. 2013 Nov;56(11):2498-506. doi: 10.1007/s00125-013-3029-3. Epub 2013 Aug 30.
Diabetologia. 2013.
PMID: 23989774
Free PMC article.
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The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1.
Sim MF, Dennis RJ, Aubry EM, Ramanathan N, Sembongi H, Saudek V, Ito D, O'Rahilly S, Siniossoglou S, Rochford JJ.
Sim MF, et al.
Mol Metab. 2012 Dec 26;2(1):38-46. doi: 10.1016/j.molmet.2012.11.002. eCollection 2012.
Mol Metab. 2012.
PMID: 24024128
Free PMC article.
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